Protein Alignment CG8757 and Dhrs7c

DIOPT Version :10

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001013031.2
• Gene: Dhrs7c / 68460
• MGIID: 1915710
• Length: 311
• Species: Mus musculus
• Alignment Length: 223
• Identity: 61/223 - (27%)
• Similarity: 97/223 - (43%)
• Gaps: 47/223 - (21%)

  Fly     6 NKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGL-SLEQQSR----------LH 59
            |||.|::.|.:|:|..|.|.....|..:|...:..|.:|.|.:.| |:...|:          |.
Mouse    37 NKVVVITDAISGLGKECARVFHAGGARLVLCGKNWEGLESLYATLTSVADPSKTFTPKLVLLDLS 101

  Fly    60 AIKC--DITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIE-------T 115
            .|.|  |:.:|  ||..:       |.||:|::||.:        :..|||.:.::|       .
Mouse   102 DISCVQDVAKE--VLDCY-------GCVDILINNASV--------KVKGPAHKISLELDKKIMDA 149

  Fly   116 NIMGTVYCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQ 180
            |..|.:...:....:|..|.| |.:|:||::..    ..|  :|....|.|:|.|:....:..|.
Mouse   150 NYFGPITLTKVLLPNMISRRT-GQIVLVNNIQA----KFG--IPFRTAYAASKHAVMGFFDCLRA 207

  Fly   181 EFQRHKTAVRVSTVSPGIVDTV-ILPEQ 207
            |.:.:.  |.||||||..:.:. ..|||
Mouse   208 EVEEYD--VVVSTVSPTFIRSYRASPEQ 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	61/223 (27%)
Dhrs7c	NP_001013031.2	11beta-HSD1_like_SDR_c	35..296	CDD:187593	61/223 (27%)