DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8757 and dhrs7

DIOPT Version :9

Sequence 1:	NP_648664.2	Gene:	CG8757 / 39528	FlyBaseID:	FBgn0036380	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001015708.1	Gene:	dhrs7 / 549350	XenbaseID:	XB-GENE-5838792	Length:	336	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	62/220 - (28%)
Similarity:	101/220 - (45%)	Gaps:	31/220 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGL----SLEQQSRLHAIKCDITQE 68
            |..|:|||:|||...:..|...|..:|..:||...:.:::...    |||.|..| .:..|:||.
Frog    52 VVWVTGASSGIGEELSYQLAKIGCPLVLSSRRETELLRVKQKCLEISSLEDQDIL-ILPLDMTQT 115

  Fly    69 DQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERD-----DGPAMRSTIETNIMGTVYCVRESF 128
            ....:|.:...:..|.:|:||:|||      .|:|.     :....|:.||.|.:||:...:...
Frog   116 SMHKEATEKALQHFGRIDILVNNAG------RSQRSLFVETNLDVFRALIELNYLGTISITKHVL 174

  Fly   129 RSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTAVRVST 193
            :.|..| .:|.:|.::||.|.    :|..|.|  .|.|:|.||:......|.|...:...: :|.
Frog   175 QHMIER-KQGKIVNISSVVGL----IGAPLSS--GYSASKHALQGFFNSLRTELTAYPDII-ISN 231

  Fly   194 VSPGIVDTVILP-------EQIQGI 211
            :.||.|.:.|:.       |::|.|
Frog   232 ICPGPVQSKIVENALTEECEKVQSI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	62/220 (28%)
CG8757	NP_648664.2	NADB_Rossmann	1..247	CDD:304358	62/220 (28%)
dhrs7	NP_001015708.1	11beta-HSD1_like_SDR_c	48..308	CDD:187593	62/220 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910