Protein Alignment CG8757 and RDH8

DIOPT Version :9

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 79/291 - (27%)
• Similarity: 122/291 - (41%)
• Gaps: 83/291 - (28%)

  Fly     7 KVAVVSGASAGIGAACTRALIGAGMIVVGLA----RRHERVEKLR-----------SGLSLEQQS 56
            :..::||.|:|||..          :.|.||    :|::.|..:|           :|.:|.|
Human     6 RTVLISGCSSGIGLE----------LAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQ-- 58

  Fly    57 RLHAIKCDITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDG---PAMRSTIETNIM 118
            .|...:.|:..::.|.:..  :|.| |.|||||:|||:...|.|    :|   .||::..:||..
Human    59 TLTVAQLDVCSDESVAQCL--SCIQ-GEVDVLVNNAGMGLVGPL----EGLSLAAMQNVFDTNFF 116

  Fly   119 GTVYCVRESFRSMKRRGTEGHVVIVNSVAGYQ--VPNLGPQLPSLNIYPATKFALRAMNE---IY 178
            |.|..|:.....|||| .:||:|:::||.|.|  :.|        ::|.|:||||....|   |.
Human   117 GAVRLVKAVLPGMKRR-RQGHIVVISSVMGLQGVIFN--------DVYAASKFALEGFFESLAIQ 172

  Fly   179 RQEFQRHKTAVRVSTVSPGIVDTVIL----------------PEQIQGIIKQHMPMLRS------ 221
            ..:|.     :.:|.|.||.|.|...                ||.:......::|..|.
Human   173 LLQFN-----IFISLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVG 232

  Fly   222 ---DDVADAVLWAIGT--PPNVQVHNITIKP 247
               .||..|::..|.:  ||..:..||...|
Human   233 QNPQDVVQAIVNVISSTRPPLRRQTNIRYSP 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	79/291 (27%)
		NADB_Rossmann	1..247	CDD:304358	78/289 (27%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	78/288 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810