DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8757 and dhs-6

DIOPT Version :9

Sequence 1:	NP_648664.2	Gene:	CG8757 / 39528	FlyBaseID:	FBgn0036380	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001021972.1	Gene:	dhs-6 / 3565470	WormBaseID:	WBGene00000970	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	47/212 - (22%)
Similarity:	80/212 - (37%)	Gaps:	50/212 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RWCNKVAVVSGASAGIG--AACTRALIGAGMIVVG-LARRH-----------ERVEKLRSGLSLE 53
            ::..:..:::|||.|||  .|...|..||.::|.. .|..|           |.:||...
Worm     6 KFVGRTVLITGASRGIGKEIALKLAKDGANIVVAAKTATAHPKLPGTIYSAAEEIEKAGG----- 65

  Fly    54 QQSRLHAIKC--DITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTI--E 114
                 .|:.|  |:..|..|..:.:...::.||:|:|::||..|   .|::.::....|..:  .
Worm    66 -----KALPCIVDVRDEASVKASVEEAVKKFGGIDILINNASAI---SLTDTENTEMKRYDLMHS 122

  Fly   115 TNIMGTVYCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQL-------PSLNIYPATKFALR 172
            .|..||....:.....:| .|...||:           |:.|.|       .:...|...|:.:.
Worm   123 INTRGTFLMTKTCLPYLK-SGKNPHVL-----------NISPPLLMETRWFANHVAYTMAKYGMS 175

  Fly   173 AMNEIYRQEFQRHKTAV 189
            .......:||:.|..||
Worm   176 MCVLGQHEEFRPHGIAV 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	47/212 (22%)
CG8757	NP_648664.2	NADB_Rossmann	1..247	CDD:304358	47/212 (22%)
dhs-6	NP_001021972.1	PRK08278	9..275	CDD:181349	47/209 (22%)
dhs-6	NP_001021972.1	SCP2	319..411	CDD:376720
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156021
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840