Protein Alignment CG8757 and HSD17B1

DIOPT Version :9

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001317148.1
• Gene: HSD17B1 / 3292
• HGNCID: 5210
• Length: 329
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 66/227 - (29%)
• Similarity: 101/227 - (44%)
• Gaps: 52/227 - (22%)

  Fly     8 VAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGL-SLEQQSRL----HAIKC---- 63
            |.:::|.|:|||.          .:.|.||....:..|:.:.| .|:.|.||    .|:.|
Human     5 VVLITGCSSGIGL----------HLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS 59

  Fly    64 ------DITQEDQVLKAFDWTCRQLGGVDVLVSNA--GIIGTGELSERDDGPAMRSTIETNIMGT 120
                  |:.....|..|.:....  |.|||||.||  |::|..|....|   |:.|.::.|::||
Human    60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGED---AVASVLDVNVVGT 119

  Fly   121 VYCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNE---IYRQEF 182
            |..::.....|||||: |.|::..||.|.    :|  ||..::|.|:||||..:.|   :....|
Human   120 VRMLQAFLPDMKRRGS-GRVLVTGSVGGL----MG--LPFNDVYCASKFALEGLCESLAVLLLPF 177

  Fly   183 QRHKTAVRVSTVSPGIVDTVIL------PEQI 208
            ..|.    :|.:..|.|.|..:      ||::
Human   178 GVHS----LSLIECGPVHTAFMEKVLGSPEEV 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	66/227 (29%)
		NADB_Rossmann	1..247	CDD:304358	66/227 (29%)
HSD17B1	NP_001317148.1	NADB_Rossmann	4..262	CDD:304358	66/227 (29%)
		adh_short	5..198	CDD:278532	64/218 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..329

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810