Protein Alignment CG8757 and Dhrs7l1

DIOPT Version :10

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001013116.1
• Gene: Dhrs7l1 / 299131
• RGDID: 1308036
• Length: 324
• Species: Rattus norvegicus
• Alignment Length: 253
• Identity: 63/253 - (24%)
• Similarity: 111/253 - (43%)
• Gaps: 36/253 - (14%)

  Fly     6 NKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEK-----LRSGLSLEQQSRLHAIKCDI 65
            :||..::|||:|||......|...|:.:|..|||.:.:|:     |.:| :|:::..| .:..|:
  Rat    49 DKVVWITGASSGIGEELAFQLSKLGVCLVLSARRGQELERVKRRCLENG-NLKEKDIL-VLPLDL 111

  Fly    66 TQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVYCVRESFRS 130
            ........|.....::.|.:|:||:|.| :....|.|..:....:..||.|.:|||...:.....
  Rat   112 ADTSSHDIATKTVLQEFGRIDILVNNGG-VAHASLVENTNMDIFKVLIEVNYLGTVSLTKCVLPH 175

  Fly   131 MKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTAVRVSTVS 195
            |..| .:|.:|::.|:.|. ||.     |..:.|.|:|.|||...::.|.|...: ..:.:|.:.
  Rat   176 MMER-NQGKIVVMKSLVGI-VPR-----PLCSGYAASKLALRGFFDVLRTELFDY-PGITLSMIC 232

  Fly   196 PGIVDTVILPEQIQGIIKQ----HMPMLR--------------SDDVADAVLWAIGTP 235
            ||.|.:.|......|...:    .:|:.:              ::|:.|  :|....|
  Rat   233 PGPVHSNIFQNAFTGDFTETRLPKIPLFKMETSRCVQLILVSLANDLED--IWIANQP 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	63/253 (25%)
Dhrs7l1	NP_001013116.1	11beta-HSD1_like_SDR_c	47..305	CDD:187593	63/253 (25%)