Protein Alignment CG8757 and DHRS7B

DIOPT Version :9

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: XP_011522088.1
• Gene: DHRS7B / 25979
• HGNCID: 24547
• Length: 334
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 57/202 - (28%)
• Similarity: 100/202 - (49%)
• Gaps: 17/202 - (8%)

  Fly     6 NKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRL-----HAIKCDI 65
            |.|.|::||::|:|..|.:....||..:|...|....:|:|...|:....:::     :.:..|:
Human    99 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDL 163

  Fly    66 TQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVYCVRESFRS 130
            |....::.|.....:..|.||:||:||||...|.:.:.......| .:|||..|.|...:....|
Human   164 TDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKR-VMETNYFGPVALTKALLPS 227

  Fly   131 M-KRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTAVRVSTV 194
            | |||  :||:|.::|:.|..      .:|..:.|.|:|.|.:|..:..|.|.::::  :.|:.:
Human   228 MIKRR--QGHIVAISSIQGKM------SIPFRSAYAASKHATQAFFDCLRAEMEQYE--IEVTVI 282

  Fly   195 SPGIVDT 201
            |||.:.|
Human   283 SPGYIHT 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	57/202 (28%)
		NADB_Rossmann	1..247	CDD:304358	57/202 (28%)
DHRS7B	XP_011522088.1	11beta-HSD1_like_SDR_c	97..>304	CDD:187593	57/202 (28%)
		adh_short	101..294	CDD:278532	56/200 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810