Protein Alignment CG8757 and DHRS7C

DIOPT Version :9

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001207422.1
• Gene: DHRS7C / 201140
• HGNCID: 32423
• Length: 312
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 62/224 - (27%)
• Similarity: 98/224 - (43%)
• Gaps: 48/224 - (21%)

  Fly     6 NKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGL-SLEQQSR-----------L 58
            |||.|::.|.:|:|..|.|.....|..:|...:..||:|.|...| |:...|:           |
Human    37 NKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLDL 101

  Fly    59 HAIKC--DITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIE------- 114
            ..|.|  |:.:|  ||..:       |.||:|::||.:        :..|||.:.::|
Human   102 SDISCVPDVAKE--VLDCY-------GCVDILINNASV--------KVKGPAHKISLELDKKIMD 149

  Fly   115 TNIMGTVYCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYR 179
            .|..|.:...:....:|..|.| |.:|:||::.|    ..|  :|....|.|:|.|.....:..|
Human   150 ANYFGPITLTKALLPNMISRRT-GQIVLVNNIQG----KFG--IPFRTTYAASKHAALGFFDCLR 207

  Fly   180 QEFQRHKTAVRVSTVSPGIVDTV-ILPEQ 207
            .|.:.:.  |.:|||||..:.:. :.|||
Human   208 AEVEEYD--VVISTVSPTFIRSYHVYPEQ 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	62/224 (28%)
		NADB_Rossmann	1..247	CDD:304358	62/224 (28%)
DHRS7C	NP_001207422.1	11beta-HSD1_like_SDR_c	35..297	CDD:187593	62/224 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900