DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8757 and Hsd17b1

DIOPT Version :9

Sequence 1:NP_648664.2 Gene:CG8757 / 39528 FlyBaseID:FBgn0036380 Length:252 Species:Drosophila melanogaster
Sequence 2:NP_034605.1 Gene:Hsd17b1 / 15485 MGIID:105077 Length:344 Species:Mus musculus


Alignment Length:223 Identity:62/223 - (27%)
Similarity:95/223 - (42%) Gaps:47/223 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 VAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGL-SLEQQ--------------SR 57
            |.:::|.|:|||.          .:.|.||....:..|:.:.| .|:.|              ..
Mouse     5 VVLITGCSSGIGM----------HLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGS 59

  Fly    58 LHAIKCDITQEDQVLKAFDWTCRQLGGVDVLVSNA--GIIGTGELSERDDGPAMRSTIETNIMGT 120
            |..::.|:.....|..|  ..|...|.|||||.||  |:.|..|..|.:   |:.:.::.|::||
Mouse    60 LEILELDVRDSKSVAAA--QACVTEGRVDVLVCNAGRGLFGPLEAHELN---AVGAVLDVNVLGT 119

  Fly   121 VYCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNE---IYRQEF 182
            :..::.....||||.: |.|::..||.|.    :|  ||...:|.|:||||..:.|   |....|
Mouse   120 IRMLQAFLPDMKRRHS-GRVLVTASVGGL----MG--LPFHEVYCASKFALEGLCESLAILLPLF 177

  Fly   183 QRHKTAVRVSTVSPGIVDTVILPEQIQG 210
                 .|.||.:..|.|.|....:.:.|
Mouse   178 -----GVHVSLIECGAVHTAFYEKLVGG 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8757NP_648664.2 YdfG 1..252 CDD:226674 62/223 (28%)
NADB_Rossmann 1..247 CDD:304358 62/223 (28%)
Hsd17b1NP_034605.1 NADB_Rossmann 4..260 CDD:304358 62/223 (28%)
adh_short 5..192 CDD:278532 60/213 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1205
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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