DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8757 and hsd11b1l.2

DIOPT Version :9

Sequence 1:	NP_648664.2	Gene:	CG8757 / 39528	FlyBaseID:	FBgn0036380	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_004910661.1	Gene:	hsd11b1l.2 / 100038278	XenbaseID:	XB-GENE-5834068	Length:	291	Species:	Xenopus tropicalis

Alignment Length:	204	Identity:	57/204 - (27%)
Similarity:	96/204 - (47%)	Gaps:	26/204 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDITQEDQ- 70
            |..:::|:|.|||..........|..::..||||:|::::.:     |..:|.|...|....|.
Frog    34 KRVLITGSSTGIGEQIAYEFAQMGAHIMLTARRHQRLQEVAN-----QCLKLGAASADYVASDMG 93

  Fly    71 VLKAFDW----TCRQLGGVDVLVSNAGIIGTGELS----ERDDGPAMRSTIETNIMGTVYCVRES 127
            .|.:..:    |.::|||:|.||.|.  || |..|    :.|..|.:.| |..|.:..|.....:
Frog    94 NLTSAQYVAQETVKKLGGLDYLVLNH--IG-GSASFGFFKGDMDPVVGS-ITINFLSYVQLTSTA 154

  Fly   128 FRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTAVRVS 192
            .|:::.  ::|.:|:::|::|    .:|  .|....|.|:||||.......|:||...|..:.|:
Frog   155 LRALQE--SQGSIVVMSSMSG----RIG--APFTTSYCASKFALEGFYSSLRREFDLQKNNMSVT 211

  Fly   193 TVSPGIVDT 201
            ....|.:||
Frog   212 VAILGYIDT 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	57/204 (28%)
CG8757	NP_648664.2	NADB_Rossmann	1..247	CDD:304358	57/204 (28%)
hsd11b1l.2	XP_004910661.1	11beta-HSD1_like_SDR_c	31..280	CDD:187593	57/204 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000