Protein Alignment CG8757 and hsd11b1l.2

DIOPT Version :10

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: XP_004910661.1
• Gene: hsd11b1l.2 / 100038278
• XenbaseID: XB-GENE-5834068
• Length: 291
• Species: Xenopus tropicalis
• Alignment Length: 207
• Identity: 57/207 - (27%)
• Similarity: 96/207 - (46%)
• Gaps: 32/207 - (15%)

  Fly     7 KVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCD------- 64
            |..:::|:|.|||..........|..::..||||:|::::.:     |..:|.|...|
 Frog    34 KRVLITGSSTGIGEQIAYEFAQMGAHIMLTARRHQRLQEVAN-----QCLKLGAASADYVASDMG 93

  Fly    65 -ITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELS----ERDDGPAMRSTIETNIMGTVYCV 124
             :|....|.:.   |.::|||:|.||.|.  || |..|    :.|..|.:.| |..|.:..|...
 Frog    94 NLTSAQYVAQE---TVKKLGGLDYLVLNH--IG-GSASFGFFKGDMDPVVGS-ITINFLSYVQLT 151

  Fly   125 RESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTAV 189
            ..:.|:::.  ::|.:|:::|::|    .:|  .|....|.|:||||.......|:||...|..:
 Frog   152 STALRALQE--SQGSIVVMSSMSG----RIG--APFTTSYCASKFALEGFYSSLRREFDLQKNNM 208

  Fly   190 RVSTVSPGIVDT 201
            .|:....|.:||
 Frog   209 SVTVAILGYIDT 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	57/207 (28%)
hsd11b1l.2	XP_004910661.1	11beta-HSD1_like_SDR_c	31..280	CDD:187593	57/207 (28%)