Protein Alignment bru3 and WHI4

DIOPT Version :10

• Sequence 1: NP_001369050.1
• Gene: bru3 / 39527
• FlyBaseID: FBgn0264001
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_010057.1
• Gene: WHI4 / 851302
• SGDID: S000002383
• Length: 649
• Species: Saccharomyces cerevisiae
• Alignment Length: 421
• Identity: 83/421 - (19%)
• Similarity: 136/421 - (32%)
• Gaps: 150/421 - (35%)

  Fly    53 TEDDVRQIFH-PFG--TIEECTILRGPDGASKGCAFVKFGSQQEAQSAITNLHGSQTMP---GAS 111
            :|..:|..|: |||  ||.:         ..:...|::....|...|.:|.......||   .|.
Yeast   251 SERSLRFSFNDPFGLETISQ---------RKESVPFLRNSISQHDLSNVTTTPVPAGMPPQKDAG 306

  Fly   112 SSLVVKYADTEKERQIRRMQQMAGHMNLLNPFVFN--------QFSPYGAYAQQQQQAALMAAAA 168
            .||::    .||:.              :|..::|        ..|.:||..|:..    |::..
Yeast   307 KSLLL----LEKDE--------------INESIWNGDELVNDVGNSSFGASLQEPP----MSSTP 349

  Fly   169 TAPGSAAAYMN-PMAALATQ------------------IPH-----GLNGTG---QPPSLP---- 202
            ....:|::..| |:..|::|                  :||     .||.:|   ...|||
Yeast   350 VMEWNASSTANIPLFQLSSQENHQSNLLPPSHHSISQDVPHIQSQPNLNNSGVIHSATSLPHYHL 414

  Fly   203 -----------------SPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVFTNGIPQTAFPGHP 250
                             |....|.::...|.||.|      .::|.....:|.|......|
Yeast   415 LNQINASTKTQSIQQSVSNVPSNLDLNLQTENGHP------QSSAPNGSSIFNNQKVNQGF---- 469

  Fly   251 LHLTIPPQGLPNGDAATLQHAFPGLPPFPGVAFPA-----VYGQ--FPQA-------LPPPLAAV 301
               .:..|     |.:|:.............||..     |.|.  ..||       :|||   .
Yeast   470 ---LVSEQ-----DTSTISRQKECSSTASASAFSKNNETNVAGSTTISQADLSLLAKVPPP---A 523

  Fly   302 APTQREDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMF--------LPFGNVISSKVFIDR 358
            .|..:.     |.|:       .|::.:||.:..:.||.|:|        |.|.|.::|....:.
Yeast   524 NPADQN-----PPCN-------TLYVGNLPPDATEQELRQLFSNQQGFRRLSFRNKMNSHGHGNG 576

  Fly   359 ATNQSKCFGFVSFDNPASAQAAIQAMNGFQI 389
            ..:...|  ||.|::.:.|..|:..:.|.|:
Yeast   577 HGHGPIC--FVEFEDVSFATRALAELYGSQL 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	17/72 (24%)
		ELAV_HUD_SF	43..404	CDD:273741	83/421 (20%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	19/79 (24%)
WHI4	NP_010057.1	RRM_scw1_like	531..624	CDD:409691	20/84 (24%)