Protein Alignment bru3 and Sxl

DIOPT Version :10

• Sequence 1: NP_001369050.1
• Gene: bru3 / 39527
• FlyBaseID: FBgn0264001
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 122/587 - (20%)
• Similarity: 203/587 - (34%)
• Gaps: 181/587 - (30%)

  Fly     9 GQPKVEFAQQVTMNRAL-----------QLKPAENESRSEHL-DRKLFVGMLSKQQTEDDVRQIF 61
            |...|:|..::...||:           :||.:......|.: |..|:|..|.:..|:|.:..||
  Fly   159 GYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIF 223

  Fly    62 HPFGTIEECTILRGP-DGASKGCAFVKFGSQQEAQSAITNLHGSQTMP-GASSSLVVKYADTEKE 124
            ..:|:|.:..|||.. .|..:|.|||::..::|||.||:.|  :..:| |.|..|.|:.|:..
  Fly   224 GKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISAL--NNVIPEGGSQPLSVRLAEEH-- 284

  Fly   125 RQIRRMQQMAGHMNLLNPFVFNQFSPYGAYAQQQQQAALMAAAATAPGSAAAYMNPMAALATQIP 189
                                                         ....||.:|:.|..:...:|
  Fly   285 ---------------------------------------------GKAKAAHFMSQMGVVPANVP 304

  Fly   190 HGLNGTGQPPSLPSPTMPNFNMGANTPNGQPGGAAAAAAAA--AAADGVFTNGIPQTAFPG---- 248
                        |.|..|..:|.|........||.....:.  |..|.:|  |:....|..
  Fly   305 ------------PPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIF--GLDSENFADLLDG 355

  Fly   249 ------HPLHLTIPPQGLPNGDAATLQHAFPGLPPFPGVAFPAVYGQFPQALPPPLAAVAPTQRE 307
                  |..:|.:.||    .....|||.                   .|||
  Fly   356 LYRRKYHYPYLXLTPQ----QQQQLLQHQ-------------------QQAL------------- 384

  Fly   308 DFLMFPGCSISGPEG--CNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRATNQSKCFGFVS 370
            .|......||....|  .|:.:||  |::...:..|..|  |||.:..:..:.:.|........:
  Fly   385 GFTSSSNNSIGNGNGNDNNMLLYH--QQYHQQQTQQQRL--GNVAAHNISPNGSNNNINTSNTNN 445

  Fly   371 FDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPYXQ-------SEFLKRNSQQPTGATTSA 428
            .:.....|..:.|::..|     .::||::|:|..... |       ..|.:::.|.....::|.
  Fly   446 INFNTIRQNGVAALHYLQ-----EQLQLQQPQDQQSQQQQPLTMPSSPPFQQQSRQSHHNGSSST 505

  Fly   429 TG----ALPTTTAF-----------------SAATPTSAV--TSVSATVTTTAHYNNLGSSFRPT 470
            .|    |:....:|                 ||.|...|:  ::.....|::.::.|..::..||
  Fly   506 LGNQLLAISNNNSFNNNSNQSNSFTGNYSNGSAFTSNGAISGSNFPNNPTSSGNFTNNSTNSNPT 570

  Fly   471 LPLPTESSNHNAHIPYTFASWRSGTYCYRNHNNNSENYSDNNNNHRNVPDSQS--QNDTSSNTNC 533
                  :|.|       |||..:|:..:.||.:.|.||:::|.|..:...|.|  .|:.:|:||.
  Fly   571 ------NSGH-------FASNLAGSSNFTNHLSGSNNYTNSNGNFTSNAASSSNFSNNAASSTNY 622

  Fly   534 SK 535
            ||
  Fly   623 SK 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	29/81 (36%)
		ELAV_HUD_SF	43..404	CDD:273741	76/376 (20%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	14/79 (18%)
Sxl	NP_001259303.1	sex-lethal	16..297	CDD:273740	41/186 (22%)