Protein Alignment bru3 and unc-75

DIOPT Version :10

• Sequence 1: NP_001369050.1
• Gene: bru3 / 39527
• FlyBaseID: FBgn0264001
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_492958.3
• Gene: unc-75 / 182722
• WormBaseID: WBGene00006807
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 464
• Identity: 207/464 - (44%)
• Similarity: 251/464 - (54%)
• Gaps: 124/464 - (26%)

  Fly    21 MNRALQLKPAENESR-----SEHLDRKLFVGMLSKQQTEDDVRQIFHPFGTIEECTILRGPDGAS 80
            ||||:|:|||:.:||     .:..|:|||:|||||||:||:||.:|..||.::|.|:|||.||||
 Worm    99 MNRAMQVKPADTDSRPASPKDKMDDKKLFIGMLSKQQSEDEVRALFATFGELDEVTVLRGADGAS 163

  Fly    81 KGCAFVKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRMQQMAGHMNLLNPFVF 145
            |||||||:....:|..||:.||||||||||||||||||||||||||.|||||||..|.:|||.:.
 Worm   164 KGCAFVKYKHGLDAHMAISALHGSQTMPGASSSLVVKYADTEKERQNRRMQQMAAQMGMLNPMLV 228

  Fly   146 NQFS-PYGAYAQQQQQAALMAAAATAPGSAAAYM--------NPMAALATQIPHGLNGTGQPPSL 201
            ||.. .|.||.|..||.:|  ||.|...::|||:        :|:..|..|
 Worm   229 NQVGMQYNAYQQVLQQQSL--AAQTNAMASAAYLPLLQQQTTDPLHVLQLQ-------------- 277

  Fly   202 PSPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVFTNGIP---------------QTAFPGHPL 251
                                  ||||||.|||:.|.:....               |:|...:|
 Worm   278 ----------------------AAAAAAQAAANPVLSQQTQQQQQQQQQLAAQLQLQSAAAQNP- 319

  Fly   252 HLTIPPQGLPNGDAA------------------------TLQHA---FPGLPPFPGVAFPAVYGQ 289
            |..:..|.|....||                        |..||   .|....:..:|..|....
 Worm   320 HYALAAQALAQQQAAQQAQAVVAHSHAQVHQHQTAQVTSTASHAQTENPAASSYGSLAAAAAAAN 384

  Fly   290 FPQAL------------------PPPLAAVAP--TQREDFLMFPGCSISGPEGCNLFIYHLPQEF 334
            :...|                  ....||..|  |.||         :.||:|||||||||||||
 Worm   385 YSSLLSGMESQHNAAAALQLAQIQQQAAAALPMVTPRE---------VLGPDGCNLFIYHLPQEF 440

  Fly   335 GDAELMQMFLPFGNVISSKVFIDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLK 399
            |||||:|||.|||:::|:|||:||||||||||||||:||..|:||||.|||||||||||||||||
 Worm   441 GDAELIQMFAPFGHIVSAKVFVDRATNQSKCFGFVSYDNIHSSQAAITAMNGFQIGMKRLKVQLK 505

  Fly   400 RPKDASRPY 408
            ||::.||||
 Worm   506 RPRNESRPY 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	55/79 (70%)
		ELAV_HUD_SF	43..404	CDD:273741	191/431 (44%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	64/77 (83%)
unc-75	NP_492958.3	RRM1_CELF3_4_5_6	24..110	CDD:410041	8/10 (80%)
		RRM2_CELF3_4_5_6	123..203	CDD:410043	55/79 (70%)
		RRM3_CELF3_4_5_6	425..503	CDD:241083	64/77 (83%)