Protein Alignment bru3 and Celf2

DIOPT Version :10

• Sequence 1: NP_001369050.1
• Gene: bru3 / 39527
• FlyBaseID: FBgn0264001
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001393872.1
• Gene: Celf2 / 14007
• MGIID: 1338822
• Length: 546
• Species: Mus musculus
• Alignment Length: 432
• Identity: 188/432 - (43%)
• Similarity: 249/432 - (57%)
• Gaps: 75/432 - (17%)

  Fly    21 MNRALQLKPAENESRSEHLDRKLFVGMLSKQQTEDDVRQIFHPFGTIEECTILRGPDGASKGCAF 85
            |:..:|:|||::|..:...|||||:||:||:..|:|:|.:|.|||.||||.|||||||.|:||||
Mouse   146 MHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAF 210

  Fly    86 VKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRM-QQMAGHMNLLNPFVFNQF- 148
            |.|.::..||:||..:|.||||.|.||.:|||:|||:|:::.||: ||:|..|..||...:...
Mouse   211 VTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLT 275

  Fly   149 -------------------SPYGAYA-----------QQQQQAALMAAAATAPGSA-AAYMNPMA 182
                               |..||::           |.|..|.|.||||.|..|| :...||::
Mouse   276 GLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLS 340

  Fly   183 ALATQIPHGLNGTGQPPSLPSPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVF--------TN 239
            :.::.:          .:|.||      :.|:|||...|.|..:..:.....|:.        .|
Mouse   341 STSSAL----------GALTSP------VAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNIN 389

  Fly   240 GIPQTAFPGHPLHLTIPPQGLPNGDAAT---LQHAFPGLPPFPGVAFPAVYGQFPQALPPPLAAV 301
            .:..|......|:..:...||.||.|.|   |..|:.|:..:...|.|.:|.   |:|....:|
Mouse   390 ALAGTINSMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYS---QSLLQQQSA- 450

  Fly   302 APTQREDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRATNQSKCF 366
            |.:|:|           ||||.|||||||||||||.:::|||:|||||||:|||||:.||.||||
Mouse   451 AGSQKE-----------GPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCF 504

  Fly   367 GFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPY 408
            ||||:|||.|||||||||||||||||||||||||.|:.|:||
Mouse   505 GFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	49/79 (62%)
		ELAV_HUD_SF	43..404	CDD:273741	176/404 (44%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	65/77 (84%)
Celf2	NP_001393872.1	RRM1_CELF1_2_Bruno	73..156	CDD:410040	4/9 (44%)
		RRM2_CELF1_2	165..245	CDD:410042	49/79 (62%)
		RRM3_CELF1_2	454..545	CDD:241082	74/101 (73%)