Protein Alignment bru3 and CELF2

DIOPT Version :9

• Sequence 1: NP_001369050.1
• Gene: bru3 / 39527
• FlyBaseID: FBgn0264001
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_024303540.1
• Gene: CELF2 / 10659
• HGNCID: 2550
• Length: 549
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 189/438 - (43%)
• Similarity: 248/438 - (56%)
• Gaps: 81/438 - (18%)

  Fly    21 MNRALQLKPAENESRSEHLDRKLFVGMLSKQQTEDDVRQIFHPFGTIEECTILRGPDGASKGCAF 85
            |:..:|:|||::|..:...|||||:||:||:..|:|:|.:|.|||.||||.|||||||.|:||||
Human   143 MHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAF 207

  Fly    86 VKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRM-QQMAGHMNLLNPFVFNQF- 148
            |.|.::..||:||..:|.||||.|.||.:|||:|||:|:::.||: ||:|..|..||...:...
Human   208 VTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLT 272

  Fly   149 -------------------SPYGAYA-----------QQQQQAALMAAAATAPGSA-AAYMNPMA 182
                               |..||::           |.|..|.|.||||.|..|| :...||::
Human   273 GLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLS 337

  Fly   183 ALATQIPHGLNGTGQPPSLPSPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVF---------- 237
            ..::.:          .:|.||      :.|:|||...|.|..:..:.....|:.
Human   338 TTSSAL----------GALTSP------VAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNIN 386

  Fly   238 ----TNGIPQTAFPGHPLHLTIPPQGLPNGDAAT---LQHAFPGLPPFPGVAFPAVYGQFPQALP 295
                |..|.|.......|:..:...||.||.|.|   |..|:.|:..:...|.|.:|.   |:|.
Human   387 ALAGTINIAQMLSGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYS---QSLL 448

  Fly   296 PPLAAVAPTQREDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRAT 360
            ...:| |.:|:|           ||||.|||||||||||||.:::|||:|||||||:|||||:.|
Human   449 QQQSA-AGSQKE-----------GPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQT 501

  Fly   361 NQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPY 408
            |.||||||||:|||.|||||||||||||||||||||||||.|:.|:||
Human   502 NLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	49/79 (62%)
		ELAV_HUD_SF	43..404	CDD:273741	177/410 (43%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	65/77 (84%)
CELF2	XP_024303540.1	RRM1_CELF1_2_Bruno	70..153	CDD:241075	4/9 (44%)
		RRM2_CELF1_2	162..242	CDD:241078	49/79 (62%)
		RRM3_CELF1_2	457..548	CDD:241082	74/101 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0144
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54704
OrthoDB	1	1.010	-	-		D1209165at2759
OrthoFinder	1	1.000	-	-		FOG0000286
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X208
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830