Protein Alignment Vps36 and Vps36

DIOPT Version :10

• Sequence 1: NP_648660.1
• Gene: Vps36 / 39523
• FlyBaseID: FBgn0086785
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_081614.1
• Gene: Vps36 / 70160
• MGIID: 1917410
• Length: 386
• Species: Mus musculus
• Alignment Length: 401
• Identity: 180/401 - (44%)
• Similarity: 265/401 - (66%)
• Gaps: 23/401 - (5%)

  Fly     1 MNRFAYVEARLSPNESFVSRDNRVKIYDGDQKTDFEDGEVVLTTHRLFW--GRPGEIARAAVTLC 63
            |:||.:....|..||:.|.:...|::|||::|..|:.|.::|:||||.|  .:..|...|
Mouse     1 MDRFVWTSGLLEINETLVIQQRGVRVYDGEEKIKFDAGTLLLSTHRLIWRDQKNNECCMA----- 60

  Fly    64 LPLSYVISVSEETTASNFFGRKTRIIMHLHPPTSDKGPGPLDTSRATHIKLSGKNGLSVEFHSAL 128
            :|||.::.:.|:...   .|:..:|::||||..|:|.|||..:|:.::|:||.|....:||:..|
Mouse    61 IPLSQIVFIEEQAAG---IGKSAKIVVHLHPAPSNKEPGPFQSSKNSYIRLSFKEHGQIEFYRRL 122

  Fly   129 RETLNARVWEILLTSEIIINGVASSPTLEPANDRLARIQKRTGIGGIERHLEAKAKATDENIALA 193
            .|.:..|.||.:..|:.:.......|         .|: :..||.||||.||.|.|.||:||:.|
Mouse   123 SEEMTQRRWETVPVSQSLQTNKGPQP---------GRV-RAVGIVGIERKLEEKRKETDKNISEA 177

  Fly   194 FQDLSVLMAMAKDMVGVSKTISSKIRKQKGEISDDETVRFKSYLMSLGIDDPVTRDNFTSNSAYF 258
            |:|||.||..||:||.:||:|::||::::|::::|||:||||||:|:||.:||||:.:.|.:.|.
Mouse   178 FEDLSKLMIKAKEMVELSKSIANKIKEKQGDVTEDETIRFKSYLLSMGIANPVTRETYGSGTQYH 242

  Fly   259 SSLARQICEMLLDPIEEQGGMMSLADVYCRVNRARGLELLSPEDLLHACEQLSG---PIRLRSFP 320
            ..||:|:..:|..|:||:||:|||.:|||.||||||:||||||||::||:.|..   |||||.|.
Mouse   243 MQLAKQLAGILQAPLEERGGIMSLTEVYCLVNRARGMELLSPEDLVNACKMLEALKLPIRLRVFD 307

  Fly   321 SGARVLQLESHDDALIAVDTLEKVEAAESLAVEELAKQLGISLLLAKERLLVAERLGKVCRDESV 385
            ||..|::|::|.:..:....||.|....||..||.||.:|:|:||||||||:||::|.:|||:||
Mouse   308 SGVMVIELQTHKEEEMVASALETVSERGSLTSEEFAKLVGMSVLLAKERLLLAEKMGHLCRDDSV 372

  Fly   386 EGLRFYPNLLL 396
            |||||||||.:
Mouse   373 EGLRFYPNLFM 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps36	NP_648660.1	PH-GRAM-like_Eap45	1..134	CDD:275408	46/134 (34%)
		EAP30	170..383	CDD:461201	116/215 (54%)
Vps36	NP_081614.1	PH-GRAM-like_Eap45	1..128	CDD:275408	44/128 (34%)
		EAP30	154..370	CDD:461201	110/218 (50%)