Protein Alignment Vps36 and vps36

DIOPT Version :10

• Sequence 1: NP_648660.1
• Gene: Vps36 / 39523
• FlyBaseID: FBgn0086785
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_596667.1
• Gene: vps36 / 2540981
• PomBaseID: SPBC3B9.09
• Length: 467
• Species: Schizosaccharomyces pombe
• Alignment Length: 458
• Identity: 100/458 - (21%)
• Similarity: 167/458 - (36%)
• Gaps: 96/458 - (20%)

  Fly    11 LSPNESFVSRDNRVKIYDGDQKT-DFEDGEVVLTTHRLFW---------------------GRPG 53
            |.|:|..:...::|.:|.||:|: ...:|.:.||...:|:                     ....
pombe    15 LDPSEEILLVQDQVGLYFGDEKSFRHNNGTLYLTKKHIFYVDSVDPKKNSLKIKISDIRDVQHTS 79

  Fly    54 EIARAAVTLCLPLSYV-----------ISVSEETTASNFFGRKTRIIMHLHPPTSDK-------- 99
            ...|::..:.|.|.:|           |:|.:........|...|..  :..|.||.
pombe    80 RYFRSSPKIRLSLRHVEKSWACKICTFINVGDPINPCRNCGVANRFT--IIKPKSDARFSQGLCT 142

  Fly   100 ----------------GPGPLDTSRATHIKLSGKNGLSVEFHSALRETLNARVWEILLTSEIIIN 148
                            |....:..|...|:||.:...|.:|:.|::..          |.|  |.
pombe   143 ACTFQNYPDLNTCEICGNQLKNVDRNQLIQLSFRGSGSSKFYEAIKSE----------TDE--IE 195

  Fly   149 GVASSPTLEPANDRLARIQKRTGIGGI---ERHLEAKAKATDENIALAFQDLSVLMAMAKDMVGV 210
            ....|...:....|.|.::|...:|||   |:..|.:.......:..|||||....::|||.:.:
pombe   196 KQRYSNKYDTKVLRKAILEKSLRMGGIHDLEQSHEMQLAKNGRTLVHAFQDLDAFFSLAKDTMSL 260

  Fly   211 SKTISSKIRKQKGEISDDETVRFKSYLMSLGIDDPVTRDNFTSN---SA----YFSSLARQICEM 268
            :...:.|:....|....|:..:..:....||    |.|.|...|   ||    |...|.:.|.|:
pombe   261 ADQFAEKMDGLTGTQQSDKVQQLLNKSNQLG----VLRGNHLDNVPVSANSRLYDIELCKSISEV 321

  Fly   269 LLDPIEEQGGMMSLADVYCRVNRARGLELLSPEDLLHACEQLSG---PIRLRSFPSGARVLQLE- 329
            |...::.....:::...:...||:|...|:.|...:.|||.:..   .|......||..:.||:
pombe   322 LRTRLKADTDTVTMTQAWAIYNRSRKANLIPPTRFVKACELIDSMEVGITTSKMNSGLILFQLKT 386

  Fly   330 -SHDDALIAVDTLEKVEAAESLAVEELAKQLGISLLLAKERLLVAERLGKVCRD---ESVEGLRF 390
             :|...|::. .||.:.  .|....:.|.:|..|:.:..|||..||..|.:.||   ||...|.:
pombe   387 SNHSGKLLSA-ILEVMN--PSTTALKCAMRLHWSIGVTLERLYQAEMDGYIVRDVYEESGSSLLY 448

  Fly   391 YPN 393
            :.|
pombe   449 WKN 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps36	NP_648660.1	PH-GRAM-like_Eap45	1..134	CDD:275408	31/179 (17%)
		EAP30	170..383	CDD:461201	58/230 (25%)
vps36	NP_596667.1	PH-like	2..103	CDD:473070	16/87 (18%)
		Vps36-NZF-N	99..>129	CDD:407195	4/31 (13%)
		RanBP2-type Zn finger	99..119	CDD:275376	2/19 (11%)
		ZnF_RBZ	141..160	CDD:197784	0/18 (0%)
		RanBP2-type Zn finger	141..158	CDD:275376	0/16 (0%)
		EAP30	220..437	CDD:461201	56/223 (25%)