Protein Alignment Tgi and VGLL4

DIOPT Version :10

• Sequence 1: NP_729916.1
• Gene: Tgi / 39521
• FlyBaseID: FBgn0036373
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_047305215.1
• Gene: VGLL4 / 9686
• HGNCID: 28966
• Length: 299
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 70/325 - (21%)
• Similarity: 109/325 - (33%)
• Gaps: 87/325 - (26%)

  Fly   221 MDSPIDMSVTTGAL-------KQRASPPPPYREPLPGTNYAANSRPSVITQAPPKREPPEQAHST 278
            |::|:|:.....:|       ::.|....|..:.||..:..::.|......:|.||:...:....
Human    10 METPLDVLSRAASLVHADDEKREAALRGEPRIQTLPVASALSSHRTGPPPISPSKRKFSMEPGDE 74

  Fly   279 DMAMCDIDEHFRRSLGENYAALFAKKSPTPTPTPTPSPSGTPKQQV-SPLAYGLPSSTSTAASQH 342
            |:. ||.|...:.|      .:|   :|....|........|:::. ||:...:..:.|...|..
Human    75 DLD-CDNDHVSKMS------RIF---NPHLNKTANGDCRRDPRERSRSPIERAVAPTMSLHGSHL 129

  Fly   343 YQ-------QQRSPLAKSGWVILEPESLQPELPPPQEEPLPLSLALHRTQTPPSPPPSATGSAPA 400
            |.       :|...|.|:......|..|.|.|.|.:           |.|..||
Human   130 YTSLPSLGLEQPLALTKNSLDASRPAGLSPTLTPGE-----------RQQNRPS----------- 172

  Fly   401 LPTAVSQVMEAAVAGRRILDTPHHTPPRYNTPPPPPPAYGIAGTTVVAPTLTPTPTPNPTPSQIP 465
                   |:..|.||.|..:..|..........|.|.:|                  ...||...
Human   173 -------VITCASAGARNCNLSHCPIAHSGCAAPGPASY------------------RRPPSAAT 212

  Fly   466 TPTPSMPAIIRVKAEPGLAAVAASSTQTPPASPTSSTNISIFTKTEASVDDHFAKALGETWKKLQ 530
            |..|.:        |.........:.:.|..:|.|   :||    ..|||||||||||:||.:::
Human   213 TCDPVV--------EEHFRRSLGKNYKEPEPAPNS---VSI----TGSVDDHFAKALGDTWLQIK 262

  Fly   531  530
            Human   263  262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tgi	NP_729916.1	VGLL4	<258..297	CDD:464585	9/38 (24%)
		TDU	282..297	CDD:197839	4/14 (29%)
		TDU	511..526	CDD:197839	11/14 (79%)
VGLL4	XP_047305215.1	VGLL4	11..233	CDD:464585	51/286 (18%)
		TDU	243..258	CDD:197839	11/14 (79%)