Protein Alignment Abp1 and COTL1

DIOPT Version :9

• Sequence 1: NP_648657.1
• Gene: Abp1 / 39520
• FlyBaseID: FBgn0036372
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_066972.1
• Gene: COTL1 / 23406
• HGNCID: 18304
• Length: 142
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 49/209 - (23%)
• Similarity: 76/209 - (36%)
• Gaps: 86/209 - (41%)

  Fly     1 MAVSFEKNRAQIVAAWKDVLDDKSDTNWSLFGYEGQTNELKVVATGDGG------VDELNEDLNS 59
            ||...:|...:  ||:..|.||.|...|..|.|:|.|     :..|:.|      :.:..:|:.
Human     1 MATKIDKEACR--AAYNLVRDDGSAVIWVTFKYDGST-----IVPGEQGAEYQHFIQQCTDDVR- 57

  Fly    60 GKIMYAFVRIE--DPKTGLNKYLLINWQGEGAPVLRKGTCANHIRDVSNLLSGAHLTINARNEDD 122
               ::||||..  |..:..:|:.||.|.||               :||.|
Human    58 ---LFAFVRFTTGDAMSKRSKFALITWIGE---------------NVSGL--------------- 89

  Fly   123 IDLDRLLKKLSTVSSAYSFKEPRGAMEEQKAPVGTNYTRVIPTKELNASVMQDFWKKEEAEEKLR 187
                                        |:|..||:.|.|   ||    |:|:|.|:....:  |
Human    90 ----------------------------QRAKTGTDKTLV---KE----VVQNFAKEFVISD--R 117

  Fly   188 QEAEKESKRLELQK 201
            :|.|::..:.||:|
Human   118 KELEEDFIKSELKK 131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abp1	NP_648657.1	ADF_drebrin_like	3..138	CDD:200437	29/142 (20%)
		DBINO	<173..>207	CDD:290603	9/29 (31%)
		SH3_Abp1_eu	476..529	CDD:212893
COTL1	NP_066972.1	ADF_coactosin_like	9..120	CDD:200438	41/188 (22%)
		Flexible and important for F-actin binding	66..75		1/8 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3655
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810