Protein Alignment Abp1 and CTTN

DIOPT Version :9

• Sequence 1: NP_648657.1
• Gene: Abp1 / 39520
• FlyBaseID: FBgn0036372
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001171669.1
• Gene: CTTN / 2017
• HGNCID: 3338
• Length: 634
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 119/549 - (21%)
• Similarity: 184/549 - (33%)
• Gaps: 225/549 - (40%)

  Fly     2 AVSFE-KNRAQIVAAWKD----------VLDDKSDTNWSLFGYEGQTNE---LKVVATGDGGVDE 52
            ||.|| :.:.:..|:.||          |..|:.|.:...|.|:|:|.:   .:..:.|.||...
Human   136 AVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYG 200

  Fly    53 LNEDLNSGKIMYAFVRIE----DPKTGLNKYLLINWQGE-GAPVLRKGTCA---NH--------- 100
            :::|    |:..:.|..|    ..|....|..:..:.|: |....|:..||   :|
Human   201 IDKD----KVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHES 261

  Fly   101 IRDVSNLLSGAHLTINARNEDDIDLDRLLKKLST------VSSAYSFKEPRGAMEEQKAPVGTNY 159
            .:|.|....|.:         .:..||:.|..||      |||||....|..|:..:.:.:..|:
Human   262 QKDYSKGFGGKY---------GVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANF 317

  Fly   160 TRVIPTKELNASVMQDFWKKEEAEEKLRQEAEKESKRLELQKLEQEQRSREEKEHKEREKLVIST 224
                                    |.|.:|.|:|.:|    |.|.|:..|..||.:|:|
Human   318 ------------------------ENLAKEKEQEDRR----KAEAERAQRMAKERQEQE------ 348

  Fly   225 TKLQPAHVPIKTSPQPLSPEKTAPGFANNLTDAERMRQARNQEARELIGSRVGAAKAMFTKHTSE 289
                                                      |||..:                |
Human   349 ------------------------------------------EARRKL----------------E 355

  Fly   290 GQLQSKLNTQPPAKPARNSIAQRINVFNQNQPQDAPVPSPPRAASPAKPLPVEAPEPVVPAPAIA 354
            .|.::|..| ||..|                   ||.|:..|                      .
Human   356 EQARAKTQT-PPVSP-------------------APQPTEER----------------------L 378

  Fly   355 PAAPVAAEVVSTIAEVEESQPVDDLPLAHESEQFSTIKRSPHSKSNSLQSQSPDETTSSNETDTA 419
            |::||..:..|..||:....||.    ..|.|...:::.:.:.:::|.|.             .|
Human   379 PSSPVYEDAASFKAELSYRGPVS----GTEPEPVYSMEAADYREASSQQG-------------LA 426

  Fly   420 VSQEQEEEVRTKVSVTVQQSQSVKSSGMSTLERNALTDLVNEDDFICQETLGDLGQRARALYDYQ 484
            .:.|...|             |.::.|....|.:...:..|           |||..|.||||||
Human   427 YATEAVYE-------------SAEAPGHYPAEDSTYDEYEN-----------DLGITAVALYDYQ 467

  Fly   485 AADETEITFDPGDVITHIDQIDEGWWQGL 513
            ||.:.||:|||.|:||:|:.||:|||:|:
Human   468 AAGDDEISFDPDDIITNIEMIDDGWWRGV 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abp1	NP_648657.1	ADF_drebrin_like	3..138	CDD:200437	38/171 (22%)
		DBINO	<173..>207	CDD:290603	9/33 (27%)
		SH3_Abp1_eu	476..529	CDD:212893	24/38 (63%)
CTTN	NP_001171669.1	HS1_rep	83..116	CDD:280396
		HS1_rep	120..155	CDD:280396	7/18 (39%)
		HS1_rep	157..192	CDD:280396	7/34 (21%)
		HS1_rep	194..228	CDD:280396	9/37 (24%)
		HS1_rep	231..266	CDD:280396	7/34 (21%)
		HS1_rep	268..>294	CDD:280396	6/34 (18%)
		TAF4	<288..>363	CDD:296797	28/166 (17%)
		SH3	459..>501	CDD:302595	24/38 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910