Protein Alignment LEP and Lep

DIOPT Version :10

• Sequence 1: NP_000221.1
• Gene: LEP / 3952
• HGNCID: 6553
• Length: 167
• Species: Homo sapiens
• Sequence 2: NP_037208.1
• Gene: Lep / 25608
• RGDID: 3000
• Length: 167
• Species: Rattus norvegicus
• Alignment Length: 167
• Identity: 137/167 - (82%)
• Similarity: 150/167 - (89%)
• Gaps: 0/167 - (0%)

Human     1 MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPG 65
            |.|..||.|||||.||.|||||||.|||||||||||||||||||||||||||::|:|||||||||
  Rat     1 MCWRPLCRFLWLWSYLSYVQAVPIHKVQDDTKTLIKTIVTRINDISHTQSVSARQRVTGLDFIPG 65

Human    66 LHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDS 130
            |||||:|||||||||||||||||:||:||:||::||||||||||:|||||||.||...||:..:|
  Rat    66 LHPILSLSKMDQTLAVYQQILTSLPSQNVLQIAHDLENLRDLLHLLAFSKSCSLPQTRGLQKPES 130

Human   131 LGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC 167
            |.||||||.|||||||||||||||||:|.||||||.|
  Rat   131 LDGVLEASLYSTEVVALSRLQGSLQDILQQLDLSPEC 167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LEP	NP_000221.1	Leptin	26..167	CDD:396559	118/140 (84%)
Lep	NP_037208.1	Leptin	26..167	CDD:396559	118/140 (84%)