Protein Alignment LEP and Lep

DIOPT Version :10

• Sequence 1: NP_000221.1
• Gene: LEP / 3952
• HGNCID: 6553
• Length: 167
• Species: Homo sapiens
• Sequence 2: NP_032519.1
• Gene: Lep / 16846
• MGIID: 104663
• Length: 167
• Species: Mus musculus
• Alignment Length: 167
• Identity: 139/167 - (83%)
• Similarity: 152/167 - (91%)
• Gaps: 0/167 - (0%)

Human     1 MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPG 65
            |.|..||.|||||.||.|||||||||||||||||||||||||||||||||||:||:|||||||||
Mouse     1 MCWRPLCRFLWLWSYLSYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSAKQRVTGLDFIPG 65

Human    66 LHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDS 130
            |||||:|||||||||||||:|||:||:||:||:|||||||||||:|||||||.||..|||:..:|
Mouse    66 LHPILSLSKMDQTLAVYQQVLTSLPSQNVLQIANDLENLRDLLHLLAFSKSCSLPQTSGLQKPES 130

Human   131 LGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC 167
            |.||||||.|||||||||||||||||:|.|||:||.|
Mouse   131 LDGVLEASLYSTEVVALSRLQGSLQDILQQLDVSPEC 167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LEP	NP_000221.1	Leptin	26..167	CDD:396559	119/140 (85%)
Lep	NP_032519.1	Leptin	26..167	CDD:396559	119/140 (85%)