Protein Alignment LEP and lep

DIOPT Version :10

• Sequence 1: NP_000221.1
• Gene: LEP / 3952
• HGNCID: 6553
• Length: 167
• Species: Homo sapiens
• Sequence 2: XP_002931881.3
• Gene: lep / 100486715
• XenbaseID: XB-GENE-980661
• Length: 169
• Species: Xenopus tropicalis
• Alignment Length: 163
• Identity: 59/163 - (36%)
• Similarity: 91/163 - (55%)
• Gaps: 0/163 - (0%)

Human     5 TLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPI 69
            ::||.||:...:...:|:...:|::|.|.|.:|::|||.:........|..|:.||||||....:
 Frog     7 SVCGILWMLLPVCQGRAIKADRVKNDAKMLARTLITRIQEHPIQFLFPSNLKINGLDFIPDEQVL 71

Human    70 LTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGV 134
            .:|..||:||.|:|:|.:|:|..||.|:.:|:||||.||.:|.....|.....:..:|..:|...
 Frog    72 ESLESMDETLEVFQKIFSSLPLENVDQMLSDMENLRSLLQLLGNIMGCTTRKPTQCDTQVNLTEE 136

Human   135 LEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC 167
            ...:.|:||.|||.|||.||..::..||....|
 Frog   137 YAKAPYTTEKVALDRLQKSLHSIVKHLDHITDC 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LEP	NP_000221.1	Leptin	26..167	CDD:396559	53/140 (38%)
lep	XP_002931881.3	Leptin	28..169	CDD:396559	53/140 (38%)