DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stv and BAG5

DIOPT Version :9

Sequence 1:	NP_001097600.1	Gene:	stv / 39518	FlyBaseID:	FBgn0086708	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001015048.1	Gene:	BAG5 / 9529	HGNCID:	941	Length:	447	Species:	Homo sapiens

Alignment Length:	176	Identity:	42/176 - (23%)
Similarity:	76/176 - (43%)	Gaps:	32/176 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 EPIINAHKEIPNQNAPPSAQAQAQAQAYAQAQPQAHAAPQQHN----RPTPLNTQAQPEQQVPVE 451
            |.::...:||.|:    ..|||..::.|..::.:......|.:    ...|...:|:....:.|:
Human   280 EKVLKRMREIKNE----LLQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQ 340

  Fly   452 G-----------------AAGLPPQTPHTLNSINKIQDIQRDVLELMGKVEQFKGTREEKEYAYL 499
            .                 |....|......|.:..:.:||       |:|..|.|.|.:|.|..|
Human   341 TLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQ-------GEVLSFDGNRTDKNYIRL 398

  Fly   500 DEMLTRNLLKLDTIDTNGKDSIRLARKEAIKCIQASINVLEAKAEE 545
            :|:||:.||.||.:|..|::..:.|||:|::..|..::.|:.|::|
Human   399 EELLTKQLLALDAVDPQGEEKCKAARKQAVRLAQNILSYLDLKSDE 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stv	NP_001097600.1	BAG	470..541	CDD:280360	25/70 (36%)
BAG5	NP_001015048.1	BAG	9..86	CDD:214591
		BAG	182..260	CDD:214591
		BAG	275..350	CDD:214591	12/73 (16%)
		BAG	365..442	CDD:214591	26/83 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158662
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4361
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12329
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930