DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stv and Bag5

DIOPT Version :9

Sequence 1:	NP_001097600.1	Gene:	stv / 39518	FlyBaseID:	FBgn0086708	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001311409.1	Gene:	Bag5 / 70369	MGIID:	1917619	Length:	447	Species:	Mus musculus

Alignment Length:	174	Identity:	45/174 - (25%)
Similarity:	80/174 - (45%)	Gaps:	28/174 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 EPIINAHKEIPNQNAPPSAQAQAQAQAYAQAQPQAHAAPQQHN----RPTPLNTQAQPEQQVPV- 450
            |.::...:||.|:    ..|||:..:.|.:|:.:......|.:    ...|...:|:....:.|
Mouse   280 ENVLKRMREIKNE----LLQAQSPPELYLRAKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQ 340

  Fly   451 ------------EGAAGLP--PQTPHTLNSINKIQDIQRDVLELMGKVEQFKGTREEKEYAYLDE 501
                        |.....|  ...||     ..:.:|..::.|::|:|..|.|.|.:|.|..|:|
Mouse   341 ILITYLDLKEALEKRKLFPCEEHPPH-----KAVWEILGNLSEILGEVLSFGGNRTDKNYIRLEE 400

  Fly   502 MLTRNLLKLDTIDTNGKDSIRLARKEAIKCIQASINVLEAKAEE 545
            :||:.||.||.:|..|::..:.|||:|:|..|..::.|:.|::|
Mouse   401 LLTKQLLALDAVDPQGEEKCKAARKQAVKLAQNILSYLDMKSDE 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stv	NP_001097600.1	BAG	470..541	CDD:280360	26/70 (37%)
Bag5	NP_001311409.1	BAG	9..86	CDD:214591
		BAG	182..260	CDD:214591
		BAG	275..350	CDD:214591	13/73 (18%)
		BAG	366..442	CDD:214591	27/80 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849061
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4361
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12329
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930