Protein Alignment CG10089 and STYXL2

DIOPT Version :9

• Sequence 1: NP_001261803.1
• Gene: CG10089 / 39517
• FlyBaseID: FBgn0036369
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_001073895.1
• Gene: STYXL2 / 92235
• HGNCID: 25034
• Length: 1158
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 112/467 - (23%)
• Similarity: 179/467 - (38%)
• Gaps: 131/467 - (28%)

  Fly     3 WH-MGKVLPGLYVGNYRDSKDHAQLERFKISHII-AIHDSPRRLLPDKH------YLCVMASDTP 59
            |: :.:|.|.:::.....:.:..:|:|..|:||: |.|.:.....|:.:      ||.|...|.|
Human   131 WNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFP 195

  Fly    60 DQNLSQYFSVCNDFIHAARLR-EGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRA 123
            :.::||:|...::|:..|.|. .|.||:....|:|||..:.|||:|...::...|||..||..||
Human   196 EVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRA 260

  Fly   124 VANPNAGFQSQLQEFEQFKLSEERRRLRERFPSSALEQLDRTKVATALDNYQELLQNRDICEGNC 188
            : .||.||..||:|..: ||.|||.                       ::|..        ||..
Human   261 I-YPNEGFLKQLRELNE-KLMEERE-----------------------EDYGR--------EGGS 292

  Fly   189 SRGEKCPTGVCNMDPTKGLFRRRPSNASTHSRLRAQSSNANASSSSLSVSSAAAQSCPTSPKNSP 253
            :..|: ..|..:|           ..|..|: |..:..:.:||..|.|....|.|:      :.|
Human   293 AEAEE-GEGTGSM-----------LGARVHA-LTVEEEDDSASHLSGSSLGKATQA------SKP 338

  Fly   254 LPIV------------RRSVG--NERIPEDEIVLEQPPTTSREAAEYAAAFEDARREQEQRQLQQ 304
            |.::            ::..|  ::::|:|        .....:|......|:...|..:|.:|:
Human   339 LTLIDEEEEEKLYEQWKKGQGLLSDKVPQD--------GGGWRSASSGQGGEELEDEDVERIIQE 395

  Fly   305 QQQLSRSQRSP--------RPVNSSREAPRVSSAGSRR----ESAAREGNGS------------- 344
            .|  ||::|..        |......|:...||.|.||    ||:|.|...|
Human   396 WQ--SRNERYQAEGYRRWGREEEKEEESDAGSSVGRRRRTLSESSAWESVSSHDIWVLKQQLELN 458

  Fly   345 ---------AQLQRSASTVSGFGVR----PRSSPAGLHAYT----GSVPSSVHGSRVDLRDAD-- 390
                     |....|.||...:..|    .:.:....||.:    .:..||..||||...|.|
Human   459 RPDHGRRRRADSMSSESTWDAWNERLLEIEKEASRRYHAKSKREEAADRSSEAGSRVREDDEDSV 523

  Fly   391 --KGSAIYLGCS 400
              :.|:.|..||
Human   524 GSEASSFYNFCS 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	46/143 (32%)
STYXL2	NP_001073895.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		DSPc	133..275	CDD:238073	46/142 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..303		8/54 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..337		6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..392		5/39 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	407..444		11/36 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	492..527		10/34 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	559..582
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..622
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	873..915
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	940..1135

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820