DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10089 and Dusp10

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_071302.2	Gene:	Dusp10 / 63953	MGIID:	1927070	Length:	483	Species:	Mus musculus

Alignment Length:	148	Identity:	53/148 - (35%)
Similarity:	80/148 - (54%)	Gaps:	15/148 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NWHMGKVLPGLYVGNYRDSKDHAQLERFKISHIIAI--HDSPRRLLPDKH-------YLCVMASD 57
            |..:..:||.|::||.:|::|...::|..|.::|.:  |      ||..|       |..:.|:|
Mouse   320 NAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTH------LPLYHYEKGLFNYKRLPATD 378

  Fly    58 TPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGR 122
            :..|||.|||....:||..|......:||||.||:|||.|:.:||:|..|.:...:|.|.|:..|
Mouse   379 SNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 443

  Fly   123 AVANPNAGFQSQLQEFEQ 140
            .:.:||..|..||.|||:
Mouse   444 PIISPNLNFMGQLLEFEE 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	50/143 (35%)
Dusp10	NP_071302.2	DSP_MapKP	150..285	CDD:238723
		Interaction with MAP kinases. /evidence=ECO:0000250	200..216
		DSP_DUSP10	323..474	CDD:350415	52/145 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820