DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10089 and dusp8a

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_957174.1	Gene:	dusp8a / 393854	ZFINID:	ZDB-GENE-040426-1842	Length:	629	Species:	Danio rerio

Alignment Length:	485	Identity:	119/485 - (24%)
Similarity:	194/485 - (40%)	Gaps:	101/485 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHII-AIHDSPR-RLLPDKHYLCVMASDTPDQNLSQYFSV 69
            ::||.||:|:.:|..:...:.:..|:::: |.:..|: ..:.:.|::.:..:|...:.|..:...
Zfish   163 RILPHLYLGSQKDVLNKDLMAQNGITYVLNASNTCPKPEFISESHFMRIPVNDNYCEKLLPWLDK 227

  Fly    70 CNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQ 134
            .|:||..|::....|::|||||:|||.|:|:||||....|:..:|.:.|:..|...:||..|..|
Zfish   228 TNEFIDKAKVSNCRVIVHCLAGISRSATIAIAYIMKTMGLSSDDAYRFVKDRRPSISPNFNFLGQ 292

  Fly   135 LQEFEQFKLSEERRRLRERFPSSALEQLDRTKVATALDNYQELL-QNRDICEGNCSRGEKCPTGV 198
            |.|||:                       ..::..||...||.| |.::..|         |.|.
Zfish   293 LLEFEK-----------------------GLRLLKALSAGQEKLEQLKEFSE---------PRGE 325

  Fly   199 CNMDPTKG----------LFRRRPS--------NASTHSRLRAQSSNANASSSSLSVSSA-AAQS 244
            .:.||.||          |..:.||        |....|..|...:|....|.||.:.|. ....
Zfish   326 SSSDPEKGRLEAEKDGTELDGKLPSPTSLQQGFNGLNLSAERILDTNRLKRSFSLDIKSVYEPNH 390

  Fly   245 CP-TSPKNS-PLPIVRRSVGNERIPEDEIVLEQPPTTSREAAEYAAAF-EDARREQEQRQLQQQQ 306
            || .:|.:: .:|.:.:....|....:.|....|.:.|...||..:.| |.:.|.:.:|:.:.
Zfish   391 CPRLAPAHTEDVPKLCKLDSPEAREVNGICQHSPVSISPGLAESPSIFPESSSRPRSRRKSKH-- 453

  Fly   307 QLSRSQRSPRPVNS-SREAPRVSSAGSRRESAAREGNGSAQLQRSASTVSGFGVRPRSSPAGLHA 370
              :.|.....||:| |....|..||   ::|::...|....|..|..|| |.|.........:.|
Zfish   454 --NGSSAGSSPVHSHSLNLGRTLSA---QKSSSLNDNLKPSLLLSLPTV-GSGPMWTKHRDTVQA 512

  Fly   371 YTGSVPSS----VHGSRVDLRDADKGSAIY---LGCSA----------------PRASTLSISSS 412
            .|...|:.    .:||.....:...|..::   ||||:                ||       .|
Zfish   513 TTPVTPTDEAPWFYGSESMNGNGGGGGMVHFPALGCSSLPGPCEAVHLREKVGEPR-------DS 570

  Fly   413 RGSSGGSAPPSPCHTPPASPRHGVKRSTSL 442
            |||....||     |..|:.:...:||..:
Zfish   571 RGSWHEDAP-----TSSAADKQFKRRSCQM 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	41/133 (31%)
dusp8a	NP_957174.1	DSP_MapKP	11..137	CDD:238723
dusp8a	NP_957174.1	DSPc	161..298	CDD:214551	42/134 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920