DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10089 and Ssh2

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_038941949.1	Gene:	Ssh2 / 303342	RGDID:	1309389	Length:	1450	Species:	Rattus norvegicus

Alignment Length:	526	Identity:	103/526 - (19%)
Similarity:	178/526 - (33%)	Gaps:	147/526 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLP---DKHYLCVMASDTPDQNLSQYFS 68
            ::...:::|:..::.:...|:...:.:|:.:........|   :.|.:.|...:..|  |..|::
  Rat   337 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATD--LLAYWN 399

  Fly    69 VCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQS 133
            ....||..|:......|:||..|:|||.:..:||.|.....|...|.:.|:..|.|..||..|..
  Rat   400 DTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYEYVKERRTVTKPNPSFMR 464

  Fly   134 QLQEFEQFKLSEERR--RLRERFPSSALE-----------QLDRTKVATALDNYQEL-------- 177
            ||:|::...|:.::|  :|......|.|.           :|::.::.|:.|...|:
  Rat   465 QLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEMTTSADQITEVKTVESLAA 529

  Fly   178 --------------------LQNRDIC---------------EGNCSRGEKCPTGVC-------- 199
                                .:.|.||               |.|.:....|.:|.|
  Rat   530 MPPVFMEHVVPQDVNQKGLRTKERVICLEFSSQEFHAGQIEDELNLNDINGCSSGCCLSESKFPL 594

  Fly   200 -NMDPTKGLFR--RRPSNASTHSRLRAQSSNANASSSSLSVSSAAAQSCPTSPKNSPLPIVRRSV 261
             |...:|.|.:  :.|..|:....|..:....:|..:.:.|.....:...:..|:.|:.
  Rat   595 DNCHASKALLQPGQAPDIANKFPDLAVEDLETDALKADVRVHLLPMEELTSRLKDLPMS------ 653

  Fly   262 GNERIPEDEIVLEQPPTTSREAAEYAAAFEDARREQEQ--RQLQQQQQLSRSQRSPRPVNSSREA 324
                 |:    ||.|    ...|...||..|...::..  ..|::..:||:..|| |..:.|
  Rat   654 -----PD----LESP----SPQAGCQAAISDFSTDRIDFFSALEKFVELSQETRS-RSFSHS--- 701

  Fly   325 PRVSSAGSRRESAAREGNGSAQLQRSASTVSGFGVRP--------RSSPAGLHAYTGSVPSSVHG 381
             |:...|..|....|              :|...:.|        |||         |:..:.|.
  Rat   702 -RIEELGGGRSEGCR--------------LSVMEMAPSEMVTDDQRSS---------SLSDTPHA 742

  Fly   382 SRVDLRDADKGSA--------IYLGCSAPRASTL--------SISSSRG--SSGGSAPPSPCHTP 428
            |.....|.|:..|        |.:...:..|.::        |||...|  ...|....:|||||
  Rat   743 SEESSVDEDQPKAVSELVSPDIIMQSHSENAISVKEIVTEIESISQGVGQVQLKGDILSNPCHTP 807

  Fly   429 PASPRH 434
            ..:..|
  Rat   808 KKNIIH 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	33/134 (25%)
Ssh2	XP_038941949.1	SSH-N	38..263	CDD:212166
		DEK_C	277..329	CDD:400903
		DSP_slingshot_2	332..475	CDD:350417	33/139 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820