DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10089 and Dusp7

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_703189.3	Gene:	Dusp7 / 235584	MGIID:	2387100	Length:	422	Species:	Mus musculus

Alignment Length:	141	Identity:	54/141 - (38%)
Similarity:	83/141 - (58%)	Gaps:	11/141 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPD--KH-----YLCVMASDTPDQNLS 64
            ::||.||:|..:||.:...|.::.|.:|:.:  :|.  ||:  :|     |..:..||...||||
Mouse   250 QILPYLYLGCAKDSTNLDVLGKYGIKYILNV--TPN--LPNAFEHGGEFTYKQIPISDHWSQNLS 310

  Fly    65 QYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNA 129
            |:|.....||..||.::..||:|||||:||||||.|||:|...:|:..:|...|:..::..:||.
Mouse   311 QFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNF 375

  Fly   130 GFQSQLQEFEQ 140
            .|..||.:||:
Mouse   376 NFMGQLLDFER 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	52/138 (38%)
Dusp7	NP_703189.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		DSP_MapKP	58..189	CDD:238723
		Interaction with MAPK1. /evidence=ECO:0000269\|PubMed:27783954	105..106
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..243
		CDC14	232..396	CDD:225297	54/141 (38%)
		DSPc	248..385	CDD:238073	52/138 (38%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q16829	334..340		4/5 (80%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910