Protein Alignment CG10089 and DUSP8

DIOPT Version :9

• Sequence 1: NP_001261803.1
• Gene: CG10089 / 39517
• FlyBaseID: FBgn0036369
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_004411.2
• Gene: DUSP8 / 1850
• HGNCID: 3074
• Length: 625
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 121/499 - (24%)
• Similarity: 178/499 - (35%)
• Gaps: 134/499 - (26%)

  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDKHYLC------VMASDTPDQNLSQ 65
            ::||.||:|:.:|..:...:.:..||:::...:|    .|...::|      |..:|...:.|..
Human   163 RILPHLYLGSQKDVLNKDLMTQNGISYVLNASNS----CPKPDFICESRFMRVPINDNYCEKLLP 223

  Fly    66 YFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAG 130
            :.....:||..|:|....|::|||||:|||.|:|:||||....::..:|.:.|:..|...:||..
Human   224 WLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFN 288

  Fly   131 FQSQLQEFEQFKLSEERRRLR----------------ERFPSSA----LEQLDRTKVATALDNYQ 175
            |..||.|:|        |.|:                |..||.|    |.:|......:|...
Human   289 FLGQLLEYE--------RSLKLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATG-- 343

  Fly   176 ELLQNRDICEGNCSRGEKCPTGVCNMDPTKGLFRRRPSNASTHSRLRA--------QSSNANASS 232
                |....||..|.|.:.|.     .||.      |:.::....||.        |.:|....|
Human   344 ----NAAAREGGLSAGGEPPA-----PPTP------PATSALQQGLRGLHLSSDRLQDTNRLKRS 393

  Fly   233 SSLSVSSAAAQS------CPTSPKNSPLPIVRRSVGNERIPEDEIVLEQPPTTSREAAEYAAAFE 291
            .||.:.||.|.|      .|..|..:|......|.....:.     |..|...|.:||      .
Human   394 FSLDIKSAYAPSRRPDGPGPPDPGEAPKLCKLDSPSGAALG-----LSSPSPDSPDAA------P 447

  Fly   292 DARREQEQRQLQQQQQLSRSQRSPRPVNSSREAPRVSSAGSRRESAARE-----GNGSAQLQR-S 350
            :||              .|.:|.|||           .|||...|.|..     |:.:.|..| .
Human   448 EAR--------------PRPRRRPRP-----------PAGSPARSPAHSLGLNFGDAARQTPRHG 487

  Fly   351 ASTVSGFGVRPRSSPAGLHAYTGSVPS----SVHGSRVDLRDADKGSAIYLGCSAPRASTLSISS 411
            .|.:|..|:.....|||..|:...:.|    |..|......:..:|:...|.....||      .
Human   488 LSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFAPFGRA------G 546

  Fly   412 SRGSSGGS---------APPSPCHT----PPASPRHGVKRSTSL 442
            :.|..|||         |.|....|    .||......:||..:
Human   547 APGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQM 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	42/137 (31%)
DUSP8	NP_004411.2	DSP_MapKP	10..137	CDD:238723
		DSPc	160..297	CDD:238073	42/137 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..586		74/338 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820