DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10089 and ssh1a

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_009299660.1	Gene:	ssh1a / 101885659	ZFINID:	ZDB-GENE-040724-201	Length:	1030	Species:	Danio rerio

Alignment Length:	466	Identity:	96/466 - (20%)
Similarity:	159/466 - (34%)	Gaps:	116/466 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDKH-YLCVMASDTPDQNLSQYFSVCNDFIH 75
            ||:|:..::.:..:|:...:.||:.:........|... |..|...|....:|..:::...:||.
Zfish   325 LYLGSEWNASNLEELQESGVGHILNVTREIDNFFPGTFCYHNVRVYDDEATDLLAHWNDTYNFIV 389

  Fly    76 AARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ 140
            .|:......|:||..|:|||.:..:||.|.......::|...|:..|::..|||.|..||.|:|.
Zfish   390 KAKKNHSKCLVHCKMGVSRSASTVIAYAMKEYGWTLEKAYNFVKQKRSITRPNASFMRQLAEYEG 454

  Fly   141 FKLSEERRRLRERFPSSALEQLDRTKVATALDNYQELLQNRDICEGNCSRGEKCP-------TGV 198
            ...:.::|..|...|.|..:             :.|..|....|..|...|:...       ..|
Zfish   455 ILDASKQRHNRLWRPDSDCD-------------HPECQQAAGPCYLNAETGDHITPDSTTPRVTV 506

  Fly   199 C------------NMDPTKGLFRRRPSNASTHSRLRAQSSNANASSSSLSVSSAAAQSCPTSP-K 250
            |            ::||      ..|.|...:.|               .:|.:|.:|.|::| :
Zfish   507 CCEPTAHSSPISLDLDP------GHPQNYHYYFR---------------RLSDSALESEPSTPVQ 550

  Fly   251 NSPLPIVRR------SVGNERIPEDEI--VLEQPP-----------TTSR-----EAAEYAAAFE 291
            ..||..|.|      .|..:.:.|||.  ..|.||           |.||     |.......|.
Zfish   551 AQPLVDVDRVYIEVADVEQDALLEDETFEAHEGPPVSHSGEGIGAQTCSRGPEPLEELRLRLEFS 615

  Fly   292 DARREQEQRQLQQQQQLSRSQRSPRPVNSSREAPRVSSAGSRRESA---AREGNGSAQLQRSAST 353
            ....|.|:...::|.::.......:.|:.......::..|....|.   ..|.|.:..|:.....
Zfish   616 TVEEEDEEEAQKEQAEMEALTEEAKRVDGKDSEELLNEKGIDLTSVNHLCNENNNNNHLKMQQIL 680

  Fly   354 VSGFGVRPRSSPAGLHAYTGSVPSSVHGSRVDLRDADKGSAIYLGCSAPRASTLSISSSRGSSGG 418
            .....|:.|.:|                          ||::   .|.|..|.||.::.||.:
Zfish   681 TESAQVKTRLAP--------------------------GSSL---ASKPIQSALSEANRRGLA-- 714

  Fly   419 SAPPSPCHTPP 429
               |.|.::.|
Zfish   715 ---PLPLNSAP 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	34/127 (27%)
ssh1a	XP_009299660.1	SSH-N	3..246	CDD:212166
		DEK_C	264..312	CDD:285919
		DSPc	317..453	CDD:238073	34/127 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920