DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10089 and ssh1

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_002932127.2	Gene:	ssh1 / 100495893	XenbaseID:	XB-GENE-6041963	Length:	975	Species:	Xenopus tropicalis

Alignment Length:	600	Identity:	111/600 - (18%)
Similarity:	203/600 - (33%)	Gaps:	191/600 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK---HYLCVMASDTPDQNLSQYFSVCNDF 73
            :|:|:..::.:..:|....:.:|:.:........|..   |.:.|...:|.|  |..:::....|
Frog   314 VYLGSEWNASNLEELHSTGVGYILNVTREIDNFFPGMFAYHNIRVYDEETTD--LLSHWNDAYHF 376

  Fly    74 IHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEF 138
            |..|:..:...|:||..|:|||.:..:||.|.....:.::|...|:..|:|..|||||..||.|:
Frog   377 ITKAKKNKSKCLVHCKMGVSRSASTVIAYAMKENGWSMEKAYNFVKQKRSVTRPNAGFMRQLLEY 441

  Fly   139 EQFKLSEERRRLR-------------------------------ERFPSS--------------- 157
            |....:.::|..:                               |..|.|
Frog   442 EGILDASKQRHNKLWMPPIFPTSYGQDTLETEFNYGLNEDYVKAETLPESYCLRHLNNPCELIEP 506

  Fly   158 -----ALEQLDR------TKVATALDN-------------YQELLQ-----------NRDICEGN 187
                 .:|:|:|      |.|.|...|             :::||.           .|.:.||:
Frog   507 LSVELEVEELERDALLGDTDVGTIRQNSPFLEGEIRKKLDFEDLLSPKRYKDDFGPAERHMKEGD 571

  Fly   188 C--------------------SRGEKCPTGVCNMDPTKGLFRR--------------RPS----- 213
            .                    |....||... ..|...|:..:              :||
Frog   572 SHIPFVPDYDEQVYKENLSSNSSKRSCPKDT-EEDAIFGILSKVKPPYPSCTDCVYPKPSEEPQK 635

  Fly   214 -------NAST----HSRLRAQSSNANASSSSLSVSSAAAQSCPTSPKNSPLPIVRRSVGNERIP 267
                   |::|    .:.|:..:|..........:....|:||| ...:||..::  ::..:: |
Frog   636 PYCEPALNSTTVCTQPTLLQHMTSAVLNRMHGDKMEEELAKSCP-GHLHSPSRVI--AITRQK-P 696

  Fly   268 EDEIVLEQPPTTSREAAEYAA----AFEDARREQEQRQL----------------QQQQQLSRSQ 312
            .|.  .|:..|.:.|...:||    :.:||::.::|:.|                |.|:.:.:.|
Frog   697 FDS--TEKQSTVTPEVDPFAAGGLLSRKDAKQYRDQKYLFFTKELEKPTMHSYLMQHQESIIQLQ 759

  Fly   313 RSPRPVNSSREAPRVSSAGSR--RESAAREGNGSA-----QLQRSASTVSGFGVRPRSSPAGLHA 370
            ::......::|..|:.|.|:.  ::....:.|.|.     .|......|...|....:....::|
Frog   760 KAGLVRKHTKELERLKSEGTSVGKDVCIEKTNCSGLYCTKDLPTYPELVQSNGQNNVAKTEMVNA 824

  Fly   371 YTG-----SVPSSVHGSRVDLRDADKGSAIYLGCSAPRASTLSISSSRGSSGGSAPPSPCHTPPA 430
            ..|     |.|:.....::.....|....|   |..|.:|::|.:.:|.||..|.
Frog   825 LDGTFQKTSTPNFCKLDQISSYTKDFLKTI---CYTPTSSSISSNLTRSSSSDSI---------- 876

  Fly   431 SPRHGVKRSTSLVKK 445
               |.|:....|||:
Frog   877 ---HSVRGMPGLVKQ 888

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	35/129 (27%)
ssh1	XP_002932127.2	SSH-N	3..235	CDD:212166
		DEK_C	249..301	CDD:400903
		DSP_slingshot_1	304..447	CDD:350418	36/134 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920