DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10089 and dusp8b

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_002665347.3	Gene:	dusp8b / 100330259	ZFINID:	ZDB-GENE-120914-3	Length:	499	Species:	Danio rerio

Alignment Length:	424	Identity:	97/424 - (22%)
Similarity:	174/424 - (41%)	Gaps:	73/424 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHII-AIHDSPR-RLLPDKHYLCVMASDTPDQNLSQYFSV 69
            ::||.||:|:.||..:...:.:..|:::: |.:..|: ..:.:.|::.:..:|:..:.|..:...
Zfish    62 RILPHLYLGSQRDVLNKEVMSQNGITYVLNASNTCPKPDFISENHFMRIPVNDSYCEKLLPWLEK 126

  Fly    70 CNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQ 134
            .|:||..|::....|::|||||:|||.|:|:||||....|:..:|.:.|:..|...:||..|..|
Zfish   127 TNEFIDKAKVSNCRVIVHCLAGISRSATIAIAYIMKTMGLSSDDAYRFVKDRRPSISPNFNFLGQ 191

  Fly   135 LQEFEQFKLSEERRRLRERFPSSALEQLDRTKVATALDNYQELLQNRDICEGNCSRGEKCPTGV- 198
            |.|||:....::......|..:|.::::  |::....::.|...|..:|.....|     ||.:
Zfish   192 LLEFERGLEMKKSLPCPIRMEASTVKEV--TEIRKMENDDQRTSQTTEITVNPPS-----PTSLQ 249

  Fly   199 -----CNMDPTKGLFRRRPSNASTHSRLRAQSSNANASSSSLSVSSAAAQSCP-TSPKNSPLPIV 257
                 .::...|.|..:|...:.:.......||:.|.:||..|.|....:.|. .:.||:
Zfish   250 KDLSSLHLSTEKILQNKRLKCSFSLDIKSVYSSSPNHNSSPNSDSENTPKICRIDNLKNT----- 309

  Fly   258 RRSVGNERIPEDEIVLEQPPTTSREAAEYAAAFEDARREQEQRQLQQQQQLSRSQRSPRPVNSSR 322
             ..||                                  |.|..:..|....|...:...:|..:
Zfish   310 -NGVG----------------------------------QSQCMIATQIGFKRLSATSLSLNLKQ 339

  Fly   323 EAPRVSSAGSRRESAAREGNGSAQLQRSASTVSGFGVRPRSSPAGLHAYTGSVPSSVHGSRVDLR 387
            |     ::|.:.::.......|..|.:|||..:..|....|:|.   ..||..|..:..:.
Zfish   340 E-----NSGLQDQNCENNKKASLLLGKSASWTTHRGSNQASTPI---TPTGDCPWFLAANL---- 392

  Fly   388 DADKGSAIYLGCSAPRASTLSISSSRGSSGGSAP 421
             |..|::.:.|.:    ||.|..|..|.||...|
Zfish   393 -APSGTSAHFGST----STYSAYSCSGQSGNPKP 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	42/133 (32%)
dusp8b	XP_002665347.3	RHOD	<13..36	CDD:294087
dusp8b	XP_002665347.3	DSPc	59..196	CDD:238073	42/133 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010