DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10089 and dusp8

DIOPT Version :9

Sequence 1:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001090693.1	Gene:	dusp8 / 100036671	XenbaseID:	XB-GENE-6458859	Length:	522	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	78/293 - (26%)
Similarity:	131/293 - (44%)	Gaps:	46/293 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHIIAI-HDSPRRL-LPDKHYLCVMASDTPDQNLSQYFSV 69
            ::||.||:|:..|..:...:.:..|:|::.: |..|:.: :||.|:|.:..:|:..:.:..:.:.
Frog   151 RILPHLYLGSQNDVMNQEVINQNGITHVLNVSHSCPQPVFIPDNHFLRIPINDSYCEKILPWLTA 215

  Fly    70 CNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQ 134
            ..:||....|..|.||:|||||:|||..||:||||.:..|:..:|.:.|:..|...:||..|..|
Frog   216 AVEFIEKVELVNGKVLVHCLAGISRSAAVAIAYIMRSMGLSLDDAYRFVKEKRPSISPNFNFLGQ 280

  Fly   135 LQEFEQFKLSEERRRLRERFPSSALEQLDRTKVATALDNYQELLQ---NRDI-CEGNCSRGEKCP 195
            |.|||        :.|....||..::......:|....:....::   |:|. |:.|||......
Frog   281 LLEFE--------KSLASTMPSGPVKASHTDSLAERKFSDHHCVKEQANKDTSCQNNCSDTAGTQ 337

  Fly   196 TGVCNMDPTKGLFRRRPSNASTHSRLRAQSSNANAS------------SSSLSVSS--------- 239
            .....:|.|| |...|..:.||.:.|..:.::...|            |.||.:.|
Frog   338 EIEVAVDATK-LNDSRTKSESTSTSLEGRFTSMGISTDQRREISSLKRSFSLDIKSVYTPLSSSV 401

  Fly   240 ---------AAAQSCPTSP-KNSPLPIVRRSVG 262
                     |.:|..|:.| .:.||.:..|.:|
Frog   402 DAHTDFCQHARSQLVPSLPVASKPLGLWDRFIG 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	45/133 (34%)
dusp8	NP_001090693.1	DSP_MapKP	11..125	CDD:238723
dusp8	NP_001090693.1	DSP_MKP_classIII	150..288	CDD:350416	47/144 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920