DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10738 and Adcy2

DIOPT Version :9

Sequence 1:NP_729905.2 Gene:CG10738 / 39516 FlyBaseID:FBgn0036368 Length:1250 Species:Drosophila melanogaster
Sequence 2:NP_112269.2 Gene:Adcy2 / 81636 RGDID:619965 Length:1095 Species:Rattus norvegicus


Alignment Length:355 Identity:94/355 - (26%)
Similarity:166/355 - (46%) Gaps:67/355 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   863 MAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQLK-------KG---------- 910
            :|:.:.|.:.... :..|. :|:.||::.:.||..:||..:|.::|       :|          
  Rat   218 LALQQTYRDTCNC-IKSRI-KLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTN 280

  Fly   911 --HKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAY 973
              |.:..:.:..|||.::||||||.::::|:|.::|..||:|:..||.|....:..:::.:||.|
  Rat   281 NFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCY 345

  Fly   974 MVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRY 1038
            ..|||||:...: ||.....|.|.:..|:.  |:|......:.:|:|:|||.|..||:||:..:|
  Rat   346 YCVSGLPISLPN-HAKNCVKMGLDMCEAIK--KVRDATGVDINMRVGVHSGNVLCGVIGLQKWQY 407

  Fly  1039 CLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQR---------- 1093
            .::...|..|:.||:.|||.::|.|   ...|:.|.|.:..|      :|.|:.|          
  Rat   408 DVWSHDVTLANHMEAGGVPGRVHIS---SVTLEHLNGAYKVE------EGDGEIRDPYLKQHLVK 463

  Fly  1094 TYWLLGEDEEART-------RRTYERSQRRGSRALNKFIQ--GTIK------QAQEQANEYGIRS 1143
            ||:::....|.|:       |.|.:.::.|.|..:.::::  |..|      .......|.|..|
  Rat   464 TYFVINPKGERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKIS 528

  Fly  1144 S----LKQKNLPRNSLTRSSSLESPKKLRF 1169
            :    :.|.|....:|...|     :|.||
  Rat   529 TTDVPMGQHNFQNRTLRTKS-----QKKRF 553

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10738NP_729905.2 PBP1_Speract_GC_like 41..441 CDD:107365
ANF_receptor 67..416 CDD:279440
PK_GC-A_B 570..853 CDD:270944
TyrKc 597..847 CDD:197581
HNOBA <862..907 CDD:285003 11/43 (26%)
CYCc 886..1078 CDD:214485 66/210 (31%)
Guanylate_cyc 913..1099 CDD:278633 62/195 (32%)
Adcy2NP_112269.2 AC_N <37..264 CDD:318454 12/47 (26%)
Guanylate_cyc 285..469 CDD:306677 62/195 (32%)
DUF1053 499..603 CDD:399378 12/60 (20%)
Guanylate_cyc 882..1081 CDD:306677
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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