Protein Alignment CG10738 and si:dkey-37g12.1

DIOPT Version :10

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_073809346.1
• Gene: si:dkey-37g12.1 / 796669
• ZFINID: ZDB-GENE-090312-145
• Length: 1067
• Species: Danio rerio
• Alignment Length: 1092
• Identity: 392/1092 - (35%)
• Similarity: 573/1092 - (52%)
• Gaps: 104/1092 - (9%)

  Fly    18 LHPLLLLLFLLAFSNFRPTHGEVFTLGYLTASQRRPGNLDYNRPGLTISGAISLAVEEVNAGRLR 82
            |..:|||:.|:..|     .|..|||  |.:...........|.|   :||: :|:..||:....
Zfish     4 LGSMLLLMALVHVS-----LGTRFTL--LISMPNTSIPFSSGRIG---AGAL-IAISSVNSSPEL 57

  Fly    83 DRGHSLQFVVAETYGEEVVSIRQTAALWTQ-QVAAYIGP--QETCVHEGRMAAAFNLPMISYYCT 144
            .|||.|.:...:....::....:.|||:.: :.:|:|||  ...|....::||.:|:.:||..|.
Zfish    58 LRGHHLDYHYVDDECNDLRGPGKIAALYNRHKYSAFIGPSCSNVCAVTAKLAAFWNIAVISPVCA 122

  Fly   145 HRDPSNKADFPTFARTRPPDTQISKSVVALLLAFNWTQVSFLYLDDASGQYQPVAETILSTLTDA 209
            .:...:|..:||..|...|.|::....|.:...|.|..:..:|  |....:....|.|.......
Zfish   123 DQQFLDKKAYPTLTRVFGPFTKLGAFFVEICKQFGWQHIGIIY--DGKPTWAIPVEGIKYQAEHN 185

  Fly   210 GVSIRDIRTWNTIYHHGFMDNPFEALVEQTYANTRIYLILGHYYEHVGLMVSLQRRGILSKGDYF 274
            .:::...:..::....|...|....|.|.... .||.:|..|......|::...::| |:.||:.
Zfish   186 NITVAKYQDIHSSLSQGSTSNWSRVLNEMAQV-ARIIVISAHGKVVRSLLIEAHKKG-LTNGDFV 248

  Fly   275 VVGIDIEQYDPAKPEKYLRGLL----LEDVEPLAVQAFQS--YLGIVPTASVSFATFANEVNKYM 333
            ..     .::|.| :|.|.|..    .:..:.:|.||:|:  :|.:...:...:..|:..|   :
Zfish   249 FF-----CFEPYK-QKVLFGSFDWEQGDSYDSMAKQAYQALFFLSLYKPSDKRYQAFSENV---I 304

  Fly   334 ERPPFNFPNPLGPFGGVKQISAEAAYLYDAVHLYAKALMEVLDSGGRPRNGSAIVAAIKGSRYRS 398
            .|...:|..   .:...:::|..||..:|.|.|||.||.|.|...|.|.:|.|:...:.....:.
Zfish   305 SRSKIDFGY---TYAQTEKVSVLAAIAHDTVWLYAHALNETLAENGNPYDGLAVTRRMWNRTIKG 366

  Fly   399 AMGYHVYIDENGDAAGNYTVLARGSVRNGRNQTVLGLRPVGTFIHRNSSLSSISKALPHQNLKLF 463
            ..| .|.||.:||...||.:   ..:|...||..:.....||:           ||:  :.:::.
Zfish   367 IQG-DVTIDASGDRELNYMM---KQIRGSNNQCQVVANYFGTY-----------KAV--KGVQIL 414

  Fly   464 SPIDWVGG--TRPAAAPRCGFGGEKCVNYTGE--ISAAIAGGALLLLSLVSLVLYRNWRYEQELD 524
                |.||  :.|..:|.|||.||.|:|...:  |:..|..|.:...:|...||||.::..:|..
Zfish   415 ----WPGGLTSPPKDSPDCGFRGELCINLERKFLIALGIIAGLMAAGTLAICVLYRKYKLPEEAS 475

  Fly   525 SLLWKIDFREVQIHENEREQQSQKQTRHLLNHLPRRLPPQSTHPLIRTSQVSLSSNPDADFRYTT 589
            .:||.|:..:|.:.|:......:|..|              :.||..:.:..:.|..|....:.|
Zfish   476 KMLWTINANDVIMMEHHSSTVPEKSHR--------------SKPLQASLESIICSMQDKPSAHRT 526

  Fly   590 IFTPIGLYKGQLYAIKKVRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCT 654
                 .:|||.:.::..|..:|..:..|:..|||..||..|.|:|.||||..:.....|::|||.
Zfish   527 -----AVYKGTICSVSFVNLRSTHLNSELLAELKQFRDLTHYNLCKFIGAALETSQPFILTEYCP 586

  Fly   655 RGSLKDILENEDVKLDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGL 719
            :|||:|||:||.:|||..|..|::.||::|:.|||.||:::||.|.:|:|:||||:|:|:|||||
Zfish   587 KGSLQDILQNESIKLDWTFKFSLMLDIVKGMDYLHHSPLQYHGHLSSSSCVVDSRFVLKVTDFGL 651

  Fly   720 FAFKQGIEDSSTDMQHMSAKCLKLLYRAPELLRQG-PSSLVMGTQRGDAYSFGILLYEMHVRRGP 783
                ..:....|:....|.....||:||||||||. |::   |||:||.|||.|:..|:..||||
Zfish   652 ----NSVRRLDTEQSPGSDPWTALLWRAPELLRQSIPAN---GTQKGDVYSFAIIAQEVVYRRGP 709

  Fly   784 F--GETGLTPMQCLQKVLQPQDYLNPYRPSLQPLETAFDCVSE---CLRECWAERPEDRPDFKTI 843
            |  ..:..:|.:.:::|  .....:|.||.:...|    ||.|   .:..||.|.|.:||||..|
Zfish   710 FYIPNSHFSPREIVERV--RAGGCSPSRPYIDRAE----CVEELESLVVSCWRETPAERPDFSYI 768

  Fly   844 RTKLR---PLRKGMRPNIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVAD 905
            ||.::   |  .|:..||.|::::.||:||.|||.:|.:||.:||||||:.:.||.:||||.||.
Zfish   769 RTAIKKNSP--HGVSENILDDLLSRMEQYACNLEEIVSERTAELQEEKKRAEGLLTQMLPRSVAS 831

  Fly   906 QLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIG 970
            ||..|..|..|.|:.|:||||||.|||||||..||:|||:.||||||.||:||.:::||||||||
Zfish   832 QLIAGKTVRAETYDCVTIYFSDIEGFTAMSASLTPMQVVNVLNDLYTYFDNIIDYHNVYKVETIG 896

  Fly   971 DAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKM 1035
            ||||||||||:||||.||.|||.|||.::..:..|...|.|..:|.:|||:||||..||||||||
Zfish   897 DAYMVVSGLPIRNGDDHAKEIARMSLAIVQGLRSFHSPHVPEQQLRVRIGVHSGPCVAGVVGLKM 961

  Fly  1036 PRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMK 1087
            ||||||||||||||||||.|:|||||.|...:.|||....:....||.|.:|
Zfish   962 PRYCLFGDTVNTASRMESYGLPLKIHVSSSTKSLLDTFRNFRCELRGDIHIK 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_SAP_GC-like	41..441	CDD:380593	97/408 (24%)
		PK_GC-A_B	570..853	CDD:270944	111/291 (38%)
		HNOBA	<860..907	CDD:462234	25/46 (54%)
		CYCc	886..1078	CDD:214485	124/191 (65%)
si:dkey-37g12.1	XP_073809346.1	None