Protein Alignment CG10738 and gucy1b2

DIOPT Version :10

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_073772943.1
• Gene: gucy1b2 / 557191
• ZFINID: ZDB-GENE-130530-664
• Length: 791
• Species: Danio rerio
• Alignment Length: 702
• Identity: 189/702 - (26%)
• Similarity: 303/702 - (43%)
• Gaps: 173/702 - (24%)

  Fly   537 IHENEREQQSQKQTRHLLNHLPRRLPPQSTHPLIRTSQVSLSSNPDADFRYTTIFTPIGLYKGQL 601
            ::::|.::::.|: .|::.|:.::  .:.|....:|.|    :|.:.:
Zfish   198 LNQSEEDERTGKK-EHVVFHMVQK--EKVTKRKAQTRQ----NNSEEE----------------- 238

  Fly   602 YAIKKVRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILENED 666
              |.:|:|...:..|.||        ||:.|:                 :.|.|
Zfish   239 --ILEVKKDKEETMRRMK--------ARYANL-----------------QLCPR----------- 265

  Fly   667 VKLDNMFIASMVADIIRGVIYLHDSPIR-------------FHGALCTS---NCLVDSRWVVKLT 715
                    .....:::|.::.|....:|             ...|.|.:   :.:.||..|||.|
Zfish   266 --------KRSPWELVRSIVMLGQGNLRQSFTPSYPKTLWIEEQAFCNAFPFHIVFDSDLVVKHT 322

  Fly   716 DFGLFAFKQGIEDSSTDM-QHMSAKCLKLLYRAPELLRQGPSSLVMGTQRGDAYSFGILLYEMHV 779
            ...:..|..|::.:...: ::.:....::::....:.:...|..|:.|:|.       :|.|:..
Zfish   323 GVNIQKFVPGLQTAGIRLDEYFTIVHPEVIFNIQSIKKFINSQFVLKTRRE-------MLPEVQQ 380

  Fly   780 RRGPFGETG----LTPMQCLQKVLQPQDYL-NPYRPSLQPLETAFDCVSECLRECWAERPEDRPD 839
            .:......|    :..:.|:       .|| :|...|||.||               ||.....|
Zfish   381 NQPTLKLRGQMMWMESLNCM-------IYLCSPKLRSLQELE---------------ERGLHLAD 423

  Fly   840 FKTIRTKLRPLRKGMRPNIFDNMMAMME-KYANNLEALVDD---RTDQLQEEKKKTDALLHEMLP 900
            .....|        .|..|..|...:.| :.:|.||...::   .:..|:.||:|::.||:.|||
Zfish   424 IAQHDT--------TRDLILLNQQRLAEIELSNQLERKKEELRILSRNLEIEKQKSEKLLYAMLP 480

  Fly   901 RCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYK 965
            ..||:|||:|.:|:...::..:|.|||:|.||.:.|.|.|:|:|:.||.:|:.||.:...::|||
Zfish   481 THVANQLKEGKRVEAGEFKVCTILFSDVVTFTNICAACEPIQIVNMLNAMYSRFDRLTSIHNVYK 545

  Fly   966 VETIGDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEF--KIRHRPTNRLLLRIGIHSGPVCA 1028
            |||||||||||.|:|:.. :.||..:|..:|.:..|..|.  .|..:|   :.:|:|:|:|||.|
Zfish   546 VETIGDAYMVVGGVPVPT-NTHAERVANFALGMRIAAREVTNPITGQP---IQIRVGLHTGPVLA 606

  Fly  1029 GVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQR 1093
            ||||.||||||||||||||||||||.|||..||.|.....::...|.:..||||.|.:||||..|
Zfish   607 GVVGEKMPRYCLFGDTVNTASRMESHGVPDHIHVSPFTFSVIKDKGIFEMAERGEIEVKGKGLMR 671

  Fly  1094 TYWLL---------------------GEDEEARTRRTYERSQRRGSRALNKFIQGTIKQAQEQAN 1137
            ||:||                     .||.|..|....|.|. ....|:.|..:...|:..|..|
Zfish   672 TYFLLKNLQKSDEQIMGLVDGEMCVYQEDLEEETDDLKEVSP-EDMNAVLKVEEDAHKEVAENGN 735

  Fly  1138 EY---GIRSSLKQKNLPRNSLTR---SSSLESPKKLRFAAGSLLEHHRYHSD 1183
            .:   ...|||.......:.|.:   :.:.:||...:..      |:.:|||
Zfish   736 NHTSPPSPSSLHSDKSSSDHLIQFDITPAYDSPNDFKHL------HNGHHSD 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_SAP_GC-like	41..441	CDD:380593
		PK_GC-A_B	570..853	CDD:270944	47/304 (15%)
		HNOBA	<860..907	CDD:462234	16/50 (32%)
		CYCc	886..1078	CDD:214485	94/193 (49%)
gucy1b2	XP_073772943.1	None