Protein Alignment CG10738 and npr1b

DIOPT Version :10

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_009290669.2
• Gene: npr1b / 555911
• ZFINID: ZDB-GENE-100805-4
• Length: 1070
• Species: Danio rerio
• Alignment Length: 1092
• Identity: 415/1092 - (38%)
• Similarity: 584/1092 - (53%)
• Gaps: 150/1092 - (13%)

  Fly    65 ISGAISLAVEEVNAG-RLRDRGHSLQFVVAETYGEEVVSIRQTAALWTQQVA------AYIGP-- 120
            :..|:..|:..|||. .|..| |.::.|.|.:...:.:.....|.|....:.      |:|||
Zfish    68 VGPALDRAIARVNANPNLLPR-HRVRHVFANSEDRDGICSESMAPLMAVDLKFEHNPWAFIGPGC 131

  Fly   121 QETCVHEGRMAAAFNLPMISYYCTHRDPS----NKADFPTFARTRPPDTQISKSVVALLLAFNWT 181
            ..|....|...|.:.||||    |...|:    ....:.:...|.|...::.:..:.|...|.|.
Zfish   132 DYTSSPVGLFTAHWGLPMI----TAGAPAVAFLQMEIYTSITNTGPTHKKLGEYALHLYRHFGWN 192

  Fly   182 QVSFLYLDDA-----------SGQYQPVAETILSTLTDAGVSIRDIRTWNTIYHHGFMDNPFEAL 235
            |.|.|...|.           .|.|..:.|             .:|.|.:.::........:..|
Zfish   193 QHSLLMFSDTKMGERACYFALEGLYTEMHE-------------ENITTMDLVFEENKGPVNYSEL 244

  Fly   236 VEQTYANTRIYLILGHYYEHVGLMVSLQRRGILSKGDYFVVGIDIEQYD----PAKPEKYLRGLL 296
            :.:...:.|:..:.........|:|...:.| |.|.:|....|||..:.    |::|  :.||
Zfish   245 LHKIQGDGRVVFVCCSPDVFRQLIVHFHKAG-LPKEEYVFFYIDIFGHSFRSRPSQP--WARG-- 304

  Fly   297 LEDVEPLAVQAFQS--YLGIVPTASVSFATFANEVNKYMERPPFNFP------NPLGPFGGVKQI 353
             :..:..|.:||||  .|..:...:..:..|..::....:| .|||.      |.:.  ||
Zfish   305 -DSDDVFAKEAFQSVKILTYLEPQNQEYKDFVTDLKSDAKR-MFNFTVDDSLMNIIS--GG---- 361

  Fly   354 SAEAAYLYDAVHLYAKALMEVL-DSGGRPRNGSAIVAAIKGSRYRSAMGYHVYIDENGDAAGNYT 417
                  .||.:.||..||.|.| ||..|| :|.::...:....|....|. |.||||||...::.
Zfish   362 ------FYDGLMLYCHALNESLSDSHERP-SGESVSKRMWNRTYYGVTGL-VQIDENGDRETDFA 418

  Fly   418 VLARGSVRNGRNQTVLGLRPVGTFIHRNSSLSSISKALPHQNLKLFSPIDWVGGTRPAAAPRCGF 482
            :.....:..|..|.|....  ||....|        .||..      .|.|.||..|...|.|||
Zfish   419 LWDMADINTGDFQIVAVYN--GTQKEMN--------ILPGM------AIQWPGGKVPMDVPTCGF 467

  Fly   483 GGEK--CVNYT---GEISAAIAGGALLLLSLVSLVLYRNWRYEQELDSLLWKIDFREVQIHENER 542
            ..|.  |...|   .::.:.:....|:::..|::.:||..:.|:||.:.||:|.:.::|
Zfish   468 KNENPACRARTIAMHQMISIVLFLILIIIFTVTVFIYRKLKLEKELVAQLWRISWDDIQ------ 526

  Fly   543 EQQSQKQTRHLLNHLPRRLPPQSTHPLIRTSQVSLS---SN------PDADFRYTTIFTPIGLYK 598
                       ::||.:.|  :||     .|:::||   ||      .|.:|:   :|...|.:|
Zfish   527 -----------MSHLEKAL--RST-----GSKLTLSLRGSNYGSLLTTDGNFQ---VFAKTGYFK 570

  Fly   599 GQLYAIKKVRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILE 663
            |.:.|||.:.::.|::||::..|||.:||.:::::..|||||.|||||||::|||.||||::|||
Zfish   571 GNIVAIKYINRRRVELTRKVLFELKHMRDVQNEHLTRFIGACIDPPNICIVTEYCPRGSLQNILE 635

  Fly   664 NEDVKLDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIED 728
            |:.:.||.||..|:::||::|:.:||:|.|..||.|.:|||:||:|:|:|:||:||.:.:   .:
Zfish   636 NDSITLDWMFKYSLISDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSIR---TE 697

  Fly   729 SSTDMQHMSAKCLKLLYRAPELLRQG--PSSLVMGTQRGDAYSFGILLYEMHVRRGPFGETG--L 789
            |.|:..|  :...:.|:.||||.|..  |..   |||:||.|||||:|.|:.:|||.|...|  |
Zfish   698 SDTEDAH--SYYARKLWLAPELSRMECFPPG---GTQKGDVYSFGIILQEVALRRGVFYLEGDLL 757

  Fly   790 TPMQCLQKV-LQPQDYLNPYRPSLQPLETAFDCVSECLRECWAERPEDRPDFKTIRTKLRPLRKG 853
            :|.:.:.:| |....||   ||||.| :...:.:.:.::.||||.|.|||:|..|...||...:.
Zfish   758 SPKEIVDRVALGEWPYL---RPSLNP-QAHSEELGQLMQRCWAEEPSDRPEFSHISVLLRKQNRE 818

  Fly   854 MRPNIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHY 918
            .|.||.||:::.||:||||||.||::||....|||:|.:|||:::||..||:|||:|..|..|.:
Zfish   819 HRSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAF 883

  Fly   919 EQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPLRN 983
            :.|:||||||||||::|||.||||||..|||||||||:||.::|||||||||||||||||||:||
Zfish   884 DSVTIYFSDIVGFTSLSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRN 948

  Fly   984 GDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTA 1048
            |.||..|||.|||.||.||..|||||||..:|.|||||||||||||||||||||||||||||||:
Zfish   949 GKLHGREIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTS 1013

  Fly  1049 SRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQRTYWLLGE 1100
            |||||:|.|||||.|...|.:|.....:....||.:.|||||..||||||||
Zfish  1014 SRMESNGEPLKIHVSSATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWLLGE 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_SAP_GC-like	41..441	CDD:380593	94/412 (23%)
		PK_GC-A_B	570..853	CDD:270944	122/296 (41%)
		HNOBA	<860..907	CDD:462234	25/46 (54%)
		CYCc	886..1078	CDD:214485	135/191 (71%)
npr1b	XP_009290669.2	Periplasmic_Binding_Protein_type1	50..453	CDD:471960	99/439 (23%)
		PK_GC-A_B	544..818	CDD:270944	120/288 (42%)
		HNOBA	<818..872	CDD:462234	28/53 (53%)
		CYCc	851..1036	CDD:214485	134/184 (73%)