DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10738 and Gycbeta100B

DIOPT Version :9

Sequence 1:	NP_729905.2	Gene:	CG10738 / 39516	FlyBaseID:	FBgn0036368	Length:	1250	Species:	Drosophila melanogaster
Sequence 2:	NP_524603.2	Gene:	Gycbeta100B / 43682	FlyBaseID:	FBgn0013973	Length:	787	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	120/349 - (34%)
Similarity:	175/349 - (50%)	Gaps:	61/349 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   849 PLRKGMRPNIFDNMMAMMEKY------ANNLEALVDDRTDQLQE-------EKKKTDALLHEMLP 900
            ||....|     :::.:.||:      ..|||.|    ||:||:       ||:|||.||:.:||
  Fly   454 PLHDAAR-----DLVLLSEKFEAEYKLTKNLEML----TDKLQQTFRDLESEKQKTDRLLYSVLP 509

  Fly   901 RCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECT----PLQVVDFLNDLYTCFDSIIG-- 959
            :.||::|:....|.|:.|:.|::.||.||||....|..|    .:::|..||:|||.||::..
  Fly   510 KSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSK 574

  Fly   960 -HYDVYKVETIGDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHS 1023
             :.:||||||:||.||.|||||....| ||..:|.::|.::......|:...|..   :.|||||
  Fly   575 RNLNVYKVETVGDKYMAVSGLPDHCED-HAKCMARVALDMMDMAKNVKMGSNPVQ---ITIGIHS 635

  Fly  1024 GPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLL----DRLGGYHFAERGVI 1084
            |.|..||:|.::|||||||:|||..||.|::|||.:|:.|.:..:||    ::...:|...||.:
  Fly   636 GEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPV 700

  Fly  1085 SMKGKGDQRTYWLLGEDEEARTRRTYERSQRRGSRALNKFIQGTIKQAQEQANEYG-IRSSLKQK 1148
            .||||......|.|                   :||.:..:.||...........| :.|.|.|.
  Fly   701 IMKGKPTPMDCWFL-------------------TRATSSILGGTSSTGGSGGGGNGSLDSPLLQP 746

  Fly  1149 NLPRNSLTRSSSLESPKKLRFAAG 1172
            ..|    |..::...|...:.|||
  Fly   747 ATP----TAGAATPIPVVAQRAAG 766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365
		ANF_receptor	67..416	CDD:279440
		PK_GC-A_B	570..853	CDD:270944	2/3 (67%)
		TyrKc	597..847	CDD:197581
		HNOBA	<862..907	CDD:285003	21/57 (37%)
		CYCc	886..1078	CDD:214485	84/209 (40%)
		Guanylate_cyc	913..1099	CDD:278633	80/196 (41%)
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	24/70 (34%)
		CYCc	496..688	CDD:214485	84/195 (43%)
		Guanylate_cyc	522..714	CDD:278633	80/195 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810