Protein Alignment CG10738 and Npr3

DIOPT Version :9

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: NP_032754.2
• Gene: Npr3 / 18162
• MGIID: 97373
• Length: 536
• Species: Mus musculus
• Alignment Length: 554
• Identity: 114/554 - (20%)
• Similarity: 197/554 - (35%)
• Gaps: 126/554 - (22%)

  Fly    60 RPGLTISGAISLAVEEVNAGRLRDRGHSLQFVVAETYGEEVVSIR------------------QT 106
            |||.......:||.:::....|..|..|..|.:|........::|                  |.
Mouse    32 RPGSRRRAREALAAQKIEVLVLLPRDDSYLFSLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQV 96

  Fly   107 A---------ALWT--QQVAA--------YIGPQETCVHE----GRMAAAFNLPMISYYC----- 143
            |         ||::  .:|||        .:||  .|.:.    .|:|:.::|||:|...
Mouse    97 AYEDSDCGNRALFSLVDRVAAARGAKPDLILGP--VCEYAAAPVARLASHWDLPMLSAGALAAGF 159

  Fly   144 THRDPSNKADFPTFARTRPPDTQISKSVVALLLAFNWTQVSFLYLDD---------ASGQYQPVA 199
            .|:|    .::....|..|...::.:.::||....:|::.:.:|.||         ..|.::...
Mouse   160 QHKD----TEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQ 220

  Fly   200 ETILSTLTDAGVSIRDIRTWNTIYHHGFMDNPFEALVEQTYANTRIYLILGHYYEHVGLMVSLQR 264
            |..|.|........:|:              ..:.:|.....:.|:.::.........:|:::.|
Mouse   221 EEGLHTSAYNFDETKDL--------------DLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHR 271

  Fly   265 RGILSKGDYFVVGIDIEQYDPAKPEKYLRGLLLEDVEPLAVQAFQSY--LGIVPTASVSFATFAN 327
            .|:.| |||....|::..........:.||   :..:..|.||:.|.  :.::.|....|..|:.
Mouse   272 HGMTS-GDYAFFNIELFNSSSYGDGSWRRG---DKHDSEAKQAYSSLQTVTLLRTVKPEFEKFSM 332

  Fly   328 EVNKYMERPPFNFPNPLGPFGGVKQISAEAAYLYDAVHLYAKALMEVLDSGGRPRNGSAIVAAIK 392
            ||...:|:...|..:.:..|         ....:||:.||..||.|||.:|...::|..|:....
Mouse   333 EVKSSVEKQGLNEEDYVNMF---------VEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTW 388

  Fly   393 GSRYRSAMGYHVYIDENGDAAGNYTVLARGSVRNGRNQTVLGLRPVGTFIHRNSSLSSISKA-LP 456
            ...:....| .|.||.|||..|:::|:|......|..:.      :|.:..:.......|.. .|
Mouse   389 NRTFEGIAG-QVSIDANGDRYGDFSVVAMTDTEAGTQEV------IGDYFGKEGRFQMRSNVKYP 446

  Fly   457 HQNLKL------------FSPIDWVGGTRPAAAPRCGFGGEKCVNYTGEISAAIAGGALLLLSLV 509
            ...|||            .||....||...:|.             ||.:..|:.|..||:....
Mouse   447 WGPLKLRLDETRIVEHTNSSPCKSSGGLEESAV-------------TGIVVGALLGAGLLMAFYF 498

  Fly   510 SLVLYR---NWRYEQELDSLLWKIDFREVQIHEN 540
            ....||   ..|.:||..::....:.||..|..:
Mouse   499 FRKKYRITIERRNQQEESNIGKHRELREDSIRSH 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365	90/437 (21%)
		ANF_receptor	67..416	CDD:279440	83/405 (20%)
		PK_GC-A_B	570..853	CDD:270944
		TyrKc	597..847	CDD:197581
		HNOBA	<862..907	CDD:285003
		CYCc	886..1078	CDD:214485
		Guanylate_cyc	913..1099	CDD:278633
Npr3	NP_032754.2	PBP1_NPR_C_like	49..440	CDD:107381	85/430 (20%)
		ANF_receptor	66..419	CDD:279440	78/386 (20%)
		TM_EphA1	471..502	CDD:214014	9/43 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810