Protein Alignment CG10738 and gc2

DIOPT Version :10

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_021333059.1
• Gene: gc2 / 140425
• ZFINID: ZDB-GENE-011128-8
• Length: 1120
• Species: Danio rerio
• Alignment Length: 1200
• Identity: 353/1200 - (29%)
• Similarity: 553/1200 - (46%)
• Gaps: 242/1200 - (20%)

  Fly     7 PAPAGNYH--------SGLLHP--------------LLLLLFLLAFSNFRPTHGEVFTLGYLTAS 49
            |.|:..:|        |||..|              |.||...:.......|:.....:|.:
Zfish     2 PHPSNAFHSFLPARGTSGLRSPSQMPHFSSDPKHIYLCLLWSTIILCLLPATNAATIKVGVV--- 63

  Fly    50 QRRPGNLD----YNRPGLTISGAISLAVEEVNAGRLRDRGHSLQFVVAETYGEEVVSIRQTAALW 110
              .|.:.|    ..:||:    |..|||..:|......:|.:..:::.:...|...|..:....:
Zfish    64 --GPWSCDPIFTKAQPGV----AARLAVAHINKDPYLSQGITFDYIILDEDCETSKSFARFLGYY 122

  Fly   111 TQQVAAYIGPQET--CVHEGRMAAAFNLPMISYYCTHRDPSNKADFPTFARTRPPDTQISKSVVA 173
            | :.:.:|||...  |.....:..::|..:.|:.|...:..:....||||||.|..:.:   :::
Zfish   123 T-RASGFIGPVNPGYCEAASLLGKSWNKAVFSWSCIEHELDDVRSHPTFARTMPVPSLV---LLS 183

  Fly   174 LLLAFNWTQVSFL--------------------------YLDDASGQYQPVAETILSTLTDAGVS 212
            .:..|.|..|..:                          .:..|...:..|.:|:....     .
Zfish   184 FMRHFRWAHVGIISSSEDVWVEAAIKLANALRSHGLPVGIVTSARNDHTSVRQTLAKVR-----K 243

  Fly   213 IRDIRTWNTIYHHGFMDNPFEALVEQTYANTRI---YLILGHY--------YEHVGLMVSLQRRG 266
            :.|:|....:.|...:....:.|:.:|..:.|:   .|:...|        |.|| ...:|:...
Zfish   244 VADLRLVILVMHSVLIGGRTQKLLLETAHDMRMTDGSLVFMSYDTLFYSLPYHHV-TQPALRYNS 307

  Fly   267 ILSKGDYFVVGIDIEQYDPAKPEKYLRGLLLEDVEPLAVQAFQSYLGIVPTASVSFATFANEVNK 331
            .|.:....|:.|.||  .|.:...|              |||:.            |....|:.|
Zfish   308 KLLRAYDAVLTITIE--SPKEQSFY--------------QAFEK------------AQEDGELPK 344

  Fly   332 YMERPPFNFPNPLGPFGGVKQISAEAAYLYDAVHLYAKALMEV------LDSGGRPRNGSAIV-- 388
            :::      |..:.|..|.         :|.::...|.|:..|      :..|...:|...::
Zfish   345 HLK------PQQVSPLFGT---------IYSSIVFMAHAVQSVRAAGQWMSGGNIAQNARNLLFK 394

  Fly   389 --AAIKGSRYRSAMGYHVYIDENG---DAAGNYTVLARGSVRNGRNQTVLGLRPVGTFIHRNSSL 448
              ::::.:.....|..:|.:|.:|   :....|.:         ..||.: :|.:|..||
Zfish   395 GGSSLQANSSDFGMLDYVILDTDGFSWELQPTYRI---------EMQTDM-VRFLGRHIH----- 444

  Fly   449 SSISKALPHQNLKLFSPIDWVGGTRPAAAPR----CGF-------GGEKCVNYTGEISAAIAGGA 502
                  .|:                 |..||    |.|       ||   ||....||..:.|..
Zfish   445 ------FPY-----------------AGPPRTDSSCWFTHGIICRGG---VNLFHMISMFLLGFL 483

  Fly   503 LLLLSL------------VSLVLYRNWRYEQELDSLLWKIDFREVQIHENEREQQSQK--QTRHL 553
            .:.||:            :.||     |...::...|..:.|....:...:......|  .||..
Zfish   484 FIFLSIGCSYCIRRKINKIRLV-----RGPNKILLTLNDVTFINPSLSNKKLSVDDSKASDTRMS 543

  Fly   554 LNHLPRRLPPQSTHPLIRTSQVSLSSNPDADFRYTTIFTPIGLYKGQLYAIKKVRKKSV-DITRE 617
            ::.              |:....:||...|.:..:.    :.:|:|....:|::...:. .||..
Zfish   544 ISE--------------RSLVSPMSSQSPATYENSN----VAIYEGDWAWMKRLPYGTFRSITPN 590

  Fly   618 MKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILENEDVKLDNMFIASMVADII 682
            .....:|::|.||:||..|:|...|.....|::|:|:||||:|:|.|:|||||.||.:|::.|:|
Zfish   591 TSDVFELMKDLRHENINPFLGFFHDCGVFAIVTEFCSRGSLEDLLVNDDVKLDWMFKSSLILDLI 655

  Fly   683 RGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIEDSSTDMQHMSAKCLKLLYRA 747
            :|:.|||...: .||.|.:.||:||.|:|:|:||:|   :.:.:|  |....::......||:.|
Zfish   656 KGMKYLHHRNV-CHGRLKSRNCVVDGRFVLKITDYG---YNEVLE--SQRFPYIEPPAEDLLWTA 714

  Fly   748 PELLRQGPSSLVMGTQRGDAYSFGILLYEMHVRRGPFGETGLTPMQCLQKVLQPQDYLNPYRPSL 812
            ||:|| |....:.||..||.|||.|::.|:.:|..||.....|..:.:|||.:|....   ||.:
Zfish   715 PEILR-GSYPGLHGTHSGDVYSFSIIMQEVVMRGPPFCMLENTFDEIVQKVRKPPPMC---RPIV 775

  Fly   813 QPLETAFDCVSECLRECWAERPEDRPDFKTIRTKLRPLRKGMRPNIFDNMMAMMEKYANNLEALV 877
            .|.....:|: :.:::||.|:||.||.|..|..:.:.:.||.:.||.|:|:.|:|:|::|||.|:
Zfish   776 SPDHAPMECI-QLMKQCWNEQPEKRPTFDEIFDQFKNVNKGKKTNIIDSMLRMLEQYSSNLEELI 839

  Fly   878 DDRTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQ 942
            .:||::|:.||:||:.||.:|||..||:.||.|..|:|||:|.||:|||||||||.:||...|::
Zfish   840 RERTEELEIEKQKTEKLLTQMLPPSVAEALKLGTTVEPEHFESVSLYFSDIVGFTTISANSEPIE 904

  Fly   943 VVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKI 1007
            |||.||||||.||::||::||||||||||||||.||:|:.||:.||||||.|:|.:||||..|::
Zfish   905 VVDLLNDLYTTFDAVIGNHDVYKVETIGDAYMVASGVPVPNGNRHAAEIANMALDILSAVGTFRM 969

  Fly  1008 RHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHC-SWQCRQLLD 1071
            ||.|...:.:|||:|:||..||||||.|||||||||||.|||||||:|:|.:||. |...:.|::
Zfish   970 RHMPDVPVRIRIGLHTGPCVAGVVGLTMPRYCLFGDTVTTASRMESTGLPYRIHVHSSTVKILME 1034

  Fly  1072 RLGGYHFAERGVISMKGKGDQRTYWLLGED 1101
            ...||....|....:|||..:.||||.|.|
Zfish  1035 LKLGYRVELRARTELKGKRIEETYWLTGRD 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_SAP_GC-like	41..441	CDD:380593	77/455 (17%)
		PK_GC-A_B	570..853	CDD:270944	95/283 (34%)
		HNOBA	<860..907	CDD:462234	23/46 (50%)
		CYCc	886..1078	CDD:214485	119/192 (62%)
gc2	XP_021333059.1	PBP1_sensory_GC_DEF-like	59..440	CDD:380594	76/452 (17%)
		PK_GC-2D	551..815	CDD:270945	94/278 (34%)
		HNOBA	<824..869	CDD:462234	22/44 (50%)
		CYCc	848..1040	CDD:214485	118/191 (62%)