DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10738 and ADCY6

DIOPT Version :9

Sequence 1:NP_729905.2 Gene:CG10738 / 39516 FlyBaseID:FBgn0036368 Length:1250 Species:Drosophila melanogaster
Sequence 2:NP_001377760.1 Gene:ADCY6 / 112 HGNCID:237 Length:1168 Species:Homo sapiens


Alignment Length:233 Identity:75/233 - (32%)
Similarity:122/233 - (52%) Gaps:18/233 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   882 DQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQ----VSIYFSDIVGFT----AMSAEC 938
            ::::|.:.....|||.:||:.||.......:.:.|.|.|    |::.|:.|..|:    .:.|..
Human   935 EEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANN 999

  Fly   939 TPLQVVDFLNDLYTCFDSIIGH---YDVYKVETIGDAYMVVSGLPLRN----GDLHAAEIATMSL 996
            ..::.:..||::...||.||..   ..:.|::|||..||..|||....    |..|...:|..::
Human  1000 EGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAM 1064

  Fly   997 HLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIH 1061
            .|:..:..  |.....|...::||::.|||.|||:|.:.|:|.::|:|||.:|||:|:|||.:|.
Human  1065 RLMEQMKH--INEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQ 1127

  Fly  1062 CSWQCRQLLDRLGGYHFAERGVISMKGKGDQRTYWLLG 1099
            .:....|:| ...||....|||:.:||||:..||:|.|
Human  1128 VTTDLYQVL-AAKGYQLECRGVVKVKGKGEMTTYFLNG 1164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10738NP_729905.2 PBP1_Speract_GC_like 41..441 CDD:107365
ANF_receptor 67..416 CDD:279440
PK_GC-A_B 570..853 CDD:270944
TyrKc 597..847 CDD:197581
HNOBA <862..907 CDD:285003 8/24 (33%)
CYCc 886..1078 CDD:214485 64/206 (31%)
Guanylate_cyc 913..1099 CDD:278633 66/200 (33%)
ADCY6NP_001377760.1 AC_N <16..368 CDD:318454
Guanylate_cyc 370..554 CDD:306677
DUF1053 582..668 CDD:399378
Guanylate_cyc 970..1164 CDD:306677 65/196 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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