DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10738 and LOC101732945

DIOPT Version :9

Sequence 1:	NP_729905.2	Gene:	CG10738 / 39516	FlyBaseID:	FBgn0036368	Length:	1250	Species:	Drosophila melanogaster
Sequence 2:	XP_031761012.1	Gene:	LOC101732945 / 101732945	-ID:	-	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	526	Identity:	229/526 - (43%)
Similarity:	320/526 - (60%)	Gaps:	55/526 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   599 GQLYAIKKVRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILE 663
            |::.||||::||:..:::.:::|:|.:||..|.|:|.|||.|.:.||:.:|:|||.:|||.|:|.
Frog   213 GRIVAIKKIQKKTFTLSKTIRREVKQIRDLDHPNLCKFIGGCIEVPNVALITEYCPKGSLNDVLL 277

  Fly   664 NEDVKLDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIED 728
            :||:.|:..|..|...||.:|:.|||...: :|..|.::||::|.|||.|:||:||:.:::.  |
Frog   278 SEDIPLNWGFRFSFAYDIAQGMAYLHQHRM-YHYRLKSTNCVIDDRWVCKITDYGLYTYRKA--D 339

  Fly   729 SSTDMQHMSAKCLKLLYRAPELLRQGPSSLVMGTQR---GDAYSFGILLYEMHVRRGPF--GETG 788
            ::...:.     |..:|..||      ...|.|.::   .|.||:.|:|.|:..|..|.  .|:|
Frog   340 TNVYQER-----LVQVYMPPE------DETVSGPEKSAAADMYSYAIILLEIATRNDPVPKDESG 393

  Fly   789 LTPMQC--LQKVLQ---------PQDYLNPYRPSLQPLETAFDCVSECLRECWAERPEDRPDFKT 842
            .....|  |.::::         |.:|:                  |.:|.|.::.|..||.|:.
Frog   394 SAEHCCLPLPELIKGKSDNGCPCPSEYV------------------ELIRRCRSQNPVQRPTFEQ 440

  Fly   843 IRTKLRPLRKGMRP---NIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVA 904
            ::.:|..    |.|   :..|.||.:||||:.:||.||.:||..|..||:|||.||:.|||:.||
Frog   441 VKKQLYK----MNPHKVSPVDLMMTLMEKYSKHLEQLVAERTQDLMHEKQKTDRLLYSMLPKQVA 501

  Fly   905 DQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETI 969
            |.|::|.....:.|...:|:||||||||.:|:..||.|||||||.|||.||.||.:|||||||||
Frog   502 DDLRQGKPSQAQSYASATIFFSDIVGFTHLSSSSTPYQVVDFLNKLYTTFDDIIDNYDVYKVETI 566

  Fly   970 GDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLK 1034
            |||||||||:|..||..|.:|||:|:|.|:|....|:|.|:|..:|.:|.|||||.|.|||||.|
Frog   567 GDAYMVVSGVPKENGIRHVSEIASMALDLVSVCKTFRIPHKPNTQLKIRAGIHSGSVVAGVVGTK 631

  Fly  1035 MPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQRTYWLLG 1099
            |||||||||||||||||||:...|||.||.....||.::|||....||.:.:|||||..||||.|
Frog   632 MPRYCLFGDTVNTASRMESTSEALKIQCSSSTHDLLKQIGGYILVCRGTLQVKGKGDMTTYWLEG 696

  Fly  1100 EDEEAR 1105
            :....|
Frog   697 KKNTPR 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365
		ANF_receptor	67..416	CDD:279440
		PK_GC-A_B	570..853	CDD:270944	82/269 (30%)
		TyrKc	597..847	CDD:197581	81/263 (31%)
		HNOBA	<862..907	CDD:285003	26/44 (59%)
		CYCc	886..1078	CDD:214485	118/191 (62%)
		Guanylate_cyc	913..1099	CDD:278633	114/185 (62%)
LOC101732945	XP_031761012.1	PKc_like	212..448	CDD:419665	82/270 (30%)
		HNOBA	<448..504	CDD:400168	29/55 (53%)
		CYCc	484..674	CDD:214485	117/189 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010