Protein Alignment CG10738 and gucy2f

DIOPT Version :9

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_002931862.2
• Gene: gucy2f / 100492820
• XenbaseID: XB-GENE-480268
• Length: 1112
• Species: Xenopus tropicalis
• Alignment Length: 1096
• Identity: 360/1096 - (32%)
• Similarity: 550/1096 - (50%)
• Gaps: 167/1096 - (15%)

  Fly    68 AISLAVEEVNAGRLRDRGHSLQFVVAETYGEEVVSIRQTAALWTQQ--VAAYIGPQET--CVHEG 128
            |..||:|.:|.....|.|.|..:|:.|   |:..:.:..:...|..  .:.:|||...  |....
 Frog    79 AAKLAIERINKDASLDLGLSFNYVILE---EDCQTSKALSTFLTYSGVASGFIGPSNPGYCDAAT 140

  Fly   129 RMAAAFNLPMISYYCTHRDPSNKADFPTFARTRPPDTQISKSVVALLLAFNWTQVSFLYLDD--- 190
            .:...:|..:.|:.|.:.:..|...:||||||.|..|::..:|:..   |.|..|..:..::
 Frog   141 LLGKNWNKAVFSWACINYELDNVKSYPTFARTLPSPTRVLFNVMKY---FQWAHVGVISSNEDIW 202

  Fly   191 -ASGQYQPVAETILSTLTDAGVSIR---DIRTWNTIYHHGFMDNPFEALVE-QTYANTRIYLILG 250
             .:|  :.||..:.|.....|:.:.   |||:..            :||.: :...|.|:.::..
 Frog   203 RDTG--RKVANALRSNGLPVGIVVSMGDDIRSTQ------------QALEKVRKIDNIRMIIMCM 253

  Fly   251 HYYEHVGLMVSLQRRGI-------LSKGDYFVVGIDIEQYD-PAKPEKYLRGLLLEDVEPLAVQA 307
            |   .|.:....|:|.:       ::.|.|..|..|...|. |.....|   .:|:: .|....|
 Frog   254 H---SVLIGGQAQQRLLEVAHDLKMTDGTYVFVPYDTLYYSLPYHKTTY---DMLKN-SPNLTAA 311

  Fly   308 FQSYLGIVPTASVSFATFANEVNKYMERPPFNF---PNPLGPFGGVKQISAEAAYLYDAVHLYAK 369
            :.|.|.|  |......||.....:..|....|.   |:.:.|..|.         :|:|::..|.
 Frog   312 YDSVLTI--TVESEGKTFYEAFQEAQESGEMNANIKPSQVSPLFGT---------IYNAIYFTAY 365

  Fly   370 ALMEVLDSGGRPR---NGSAIVAAIKGSRYRSAMGYHVYI--DENGDAAGNYTVLARGSVRNGRN 429
            |    ::|..|..   :||::|   |.|:.....|::.:|  |.:|:...:|.:|......|.
 Frog   366 A----MNSSRRQGTWVSGSSLV---KHSKNMQFYGFNQWIKTDMSGNGFTDYVILDADMKTNE-- 421

  Fly   430 QTVLGLRPVGTFIHRNSSLSSISKALPHQNLKLFSPIDWVGGTRPAAAPRCGFG-GEKCVNYTGE 493
                        :||...:...:..:.:..    .||.:..|..|.....|.|. |:.|   ||.
 Frog   422 ------------LHRTYVVDMETDMVRYMG----RPIHFPNGVSPKTDSYCWFSDGKIC---TGG 467

  Fly   494 ISAAIAGGALLLLSLVSLVLYRNW---------------RYEQELDSLLWKIDFREVQIH----E 539
            |..|.|  .::.|.:|..::..|.               |...::...|..:.|...|:.    .
 Frog   468 IEPAFA--LMVFLCIVVAIISLNGLAYVIRRRINKIKLVRGPNKILLTLEDVTFINPQLSVKKLS 530

  Fly   540 NEREQQSQK-----QTRHLLNHLPRRLPPQSTHPLIRTSQVSLSSNPDADFRYTTIFTPIGLYKG 599
            |:..:.|..     .||.:.:  |.|  ..||..||..:..  :||             :.:|:|
 Frog   531 NDGSRTSDSGPVLTDTRSMKS--PMR--SGSTQSLIPATYE--NSN-------------VAIYEG 576

  Fly   600 QLYAIKK--------VRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRG 656
            ....:||        ::..:.|:...||       |.||:|:..|:|...|.....|::|:|:||
 Frog   577 DWVWMKKFPSGDFGELKPGTSDVFETMK-------DMRHENVNPFLGFFHDCGVFAIVTEFCSRG 634

  Fly   657 SLKDILENEDVKLDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFA 721
            ||:|:|.|:|||||.||.:|::.|:|:|:.|||.... .||.|.:.||:||.|:|:|:||:|
 Frog   635 SLEDLLRNQDVKLDWMFKSSLLLDLIKGMKYLHHRKF-VHGRLKSRNCVVDGRFVLKVTDYG--- 695

  Fly   722 FKQGIEDSSTDMQHMSAKCLKLLYRAPELLRQGPSSLVMGTQRGDAYSFGILLYEMHVRRGPFGE 786
            :.:.:|  :..:.|......:||:.||||||. |.|.|.|:..||.|||.:::.|:.||..||..
 Frog   696 YNEVLE--AQRIPHEEPTAYELLWTAPELLRD-PLSAVHGSFSGDVYSFSVIMQEVVVRGPPFCT 757

  Fly   787 TGLTPMQCLQKVLQPQDYLNPYRPSLQPLETAFDCVSECLRECWAERPEDRPDFKTIRTKLRPLR 851
            ...|..:.:|||.:|....   ||.:.|.....:|:. .:::||.|.|:.||.|..|..:.:.:.
 Frog   758 VEDTAEEIIQKVKKPPPLC---RPMVSPDHAPMECII-LMKKCWNEVPDRRPSFDEIFDQFKNIN 818

  Fly   852 KGMRPNIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPE 916
            ||.:.||.|:|:.|:|:|::|||.|:.:||::|:.||:||:.||.:|||..||:.||.|..|:||
 Frog   819 KGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAEALKMGCTVEPE 883

  Fly   917 HYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPL 981
            .:::|::|||||||||::||...|::|||.||||||.||::||::||||||||||||||.||||.
 Frog   884 GFDEVTLYFSDIVGFTSISAMSEPIEVVDLLNDLYTLFDAVIGNHDVYKVETIGDAYMVASGLPK 948

  Fly   982 RNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVN 1046
            |||:.||||||.|||.:||:|..||:||.|...:.:|||:||||..||||||.||||||||||||
 Frog   949 RNGNRHAAEIANMSLDILSSVGSFKMRHMPDVPVRIRIGLHSGPAVAGVVGLTMPRYCLFGDTVN 1013

  Fly  1047 TASRMESSGVPLKIHCSWQCRQLLDRLG-GYHFAERGVISMKGKGDQRTYWLLGED 1101
            |||||||:|:|.:||.:....:.|..|. ||....||...:||||.:.|:||:|::
 Frog  1014 TASRMESTGLPYRIHVNQSTVKTLRSLNEGYLLELRGRTELKGKGIEETFWLVGKE 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365	87/400 (22%)
		ANF_receptor	67..416	CDD:279440	84/375 (22%)
		PK_GC-A_B	570..853	CDD:270944	95/290 (33%)
		TyrKc	597..847	CDD:197581	92/257 (36%)
		HNOBA	<862..907	CDD:285003	22/44 (50%)
		CYCc	886..1078	CDD:214485	121/192 (63%)
		Guanylate_cyc	913..1099	CDD:278633	116/186 (62%)
gucy2f	XP_002931862.2	PBP1_sensory_GC_DEF-like	58..439	CDD:380594	89/418 (21%)
		PK_GC-2D	553..820	CDD:270945	99/301 (33%)
		HNOBA	<829..874	CDD:400168	22/44 (50%)
		CYCc	853..1044	CDD:214485	119/190 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010