Protein Alignment CG10738 and npr1

DIOPT Version :10

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_031747254.1
• Gene: npr1 / 100492092
• XenbaseID: XB-GENE-970522
• Length: 1053
• Species: Xenopus tropicalis
• Alignment Length: 1088
• Identity: 398/1088 - (36%)
• Similarity: 594/1088 - (54%)
• Gaps: 139/1088 - (12%)

  Fly    65 ISGAISLAVEEVNAGRLRDRGHSLQFVVAETYGEE-------------VVSIRQTAALWTQQVAA 116
            :..||.:|:|.:|    ||........|...:|:.             ||::   ...:|.....
 Frog    46 VGPAIHMAIERIN----RDPALLPDLRVQTFFGDSEDKDGNCSDSTAPVVAV---DLQFTHHPEV 103

  Fly   117 YIGPQETCVHE----GRMAAAFNLPMISYYCTHRDPSNKAD-FPTFARTRPPDTQISKSVVALLL 176
            ::||  .|::.    .|..|.:.:|:|:........::|:| :....||....|::.:.|..:..
 Frog   104 FLGP--GCIYTAAPVARFTAHWKVPLITVGAAAFGFNDKSDVYQYTTRTGLIPTKLGQFVGHIHQ 166

  Fly   177 AFNWTQVSFLYLDDASGQYQP---VAETILSTLTDAGVSIRDIRTWNTIYHHGFMDNP---FEAL 235
            .:||:..:.:...|:|...:|   ..|.:...|....:::.|::         |.|..   :.:|
 Frog   167 RYNWSSRAMIVYRDSSLDDRPCFFTMEGLYMELLKFNLTVLDLQ---------FKDKELTNYTSL 222

  Fly   236 VEQTYANTRIYLILGHYYEHVGLMVSLQRRGILSKGDYFVVGIDIEQY--------DPAKPEKYL 292
            :.......||..:..:......||:...|.|:.| |||....:||...        ||.:|  :.
 Frog   223 IHDIKQKGRIIYMCCYPDMFRQLMIQAWREGLCS-GDYAFFYVDIWGASLQGAIFPDPQRP--WY 284

  Fly   293 RGLLLEDVEPLAVQAFQSYLGIV--PTASVSFATFANEVNKYMERPPFNFPNPLGPFGGVKQ--- 352
            ||   :..:..|.:||::.:.|.  ...:..:..|...:::|.|.|.:           .:|
 Frog   285 RG---DPDDAKAREAFKAVMIITYKEPDNPEYREFLANLSRYSEAPFY-----------YRQEST 335

  Fly   353 -ISAEAAYLYDAVHLYAKALMEVLDSGGRPRNGSAIVAAIKGSRYRSAMGYHVYIDENGDAAGNY 416
             ::|.:|..:|:|.|||.|:.|...:|...:|.||:.:.::...:..|.|: |.||:|||...::
 Frog   336 LMNALSASFHDSVLLYAHAVNETRANGYSMKNASAVTSYMRNKSFYGASGF-VKIDDNGDRENDF 399

  Fly   417 TVLARGSVRNGRNQTVLGLRPVGTF---IHRNSSLSSISKALPHQNLKLFSPIDWVGGTRPAAAP 478
            ::...             ..|.|||   .:.|.:|..| ..||.:.      |:|.|...|...|
 Frog   400 SLWDM-------------YEPHGTFQIVYNYNGTLRKI-VPLPGRE------IEWPGNRIPRDVP 444

  Fly   479 RCGF--GGEKCVNYTG---EISAAIAGGALLLLSLVSLVLYRNWRYEQELDSLLWKIDFREVQIH 538
            .|||  ...||...:.   ||.:.:....||::::.|:.:||..|.|:||.:.||:|.:.:  ||
 Frog   445 PCGFDHSDPKCKKSSFTILEILSIVICFILLIITVSSIFIYRKLRLEKELAAELWRIRWED--IH 507

  Fly   539 ENEREQQSQKQTRHLLNHLPRRLPPQSTHPLIRTSQVSLSSNPDADFRYTTIFTPIGLYKGQLYA 603
            .:..|    |..|...:.|...|...:...|:.|         :..|:   |:.....|||.:.|
 Frog   508 TSNLE----KNLRRAGSKLTLSLRGSNYGSLLTT---------EGQFQ---IYAKTAYYKGNIIA 556

  Fly   604 IKKVRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILENEDVK 668
            :|.:.:|.:::||::..|||.:||.:::::..|:|:|.|||||||::|||.||||:||||||.:.
 Frog   557 VKHINRKRIELTRKVLFELKHMRDVQNEHLTRFVGSCIDPPNICILTEYCPRGSLQDILENESIT 621

  Fly   669 LDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIEDSSTDM 733
            ||.||..|::.||::|:::||:|.|..||.|.:|||:||||:|:|:||:||.:|:     .|.|.
 Frog   622 LDWMFRYSLINDIVKGMLFLHNSVIVTHGNLKSSNCVVDSRFVLKITDYGLASFR-----CSPDS 681

  Fly   734 QHMSAKCLKLLYRAPELLR-QGPSSLVMGTQRGDAYSFGILLYEMHVRRGPF--GETGLTPMQCL 795
            :.:.|...|.|:.:||||| :.|..  .|||:||.|||||:|.|:.:|.|.|  .....:|.:.:
 Frog   682 EDIHAYFAKKLWTSPELLRMETPPP--QGTQKGDVYSFGIILQEVALRNGVFYVDNADYSPKEII 744

  Fly   796 QKVLQPQDYLNPYRPSLQPLETAFDCVSE---CLRECWAERPEDRPDFKTIRTKLRPLRKGMRPN 857
            ::|...:      :|..:|....:..:.|   .::.||||.|.:||:|..|:.:||...:....|
 Frog   745 ERVRSRE------KPIFRPCTNLYCHIQELGQLMQRCWAEDPFERPEFNQIKVQLRKFNRESSTN 803

  Fly   858 IFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVS 922
            |.||:::.||:||||||.||:|||....|||:|.:|||:::||..||:|||:|..|..|.::.|:
 Frog   804 ILDNLLSRMEQYANNLEELVEDRTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVT 868

  Fly   923 IYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPLRNGDLH 987
            |||||||||||:|||.||:|||..|||||||||:||.::|||||||||||||||||||:|||.||
 Frog   869 IYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLH 933

  Fly   988 AAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRME 1052
            |.|:|.|||.||.||..|||||||..:|.||||||:|||||||||||||||||||||||||||||
 Frog   934 AREVARMSLALLDAVKSFKIRHRPNQQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRME 998

  Fly  1053 SSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQRTYWLLGE 1100
            |:|..||||.|.....:|:....:....||.:.|||||..|||||.||
 Frog   999 SNGEALKIHVSTATHCVLEEFNCFVLELRGDVEMKGKGKVRTYWLQGE 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_SAP_GC-like	41..441	CDD:380593	85/413 (21%)
		PK_GC-A_B	570..853	CDD:270944	110/288 (38%)
		HNOBA	<860..907	CDD:462234	26/46 (57%)
		CYCc	886..1078	CDD:214485	133/191 (70%)
npr1	XP_031747254.1	PBP1_NPR_A	27..434	CDD:380608	93/443 (21%)
		PK_GC-A_B	525..799	CDD:270944	112/298 (38%)
		HNOBA	<805..853	CDD:462234	26/47 (55%)
		CYCc	832..1017	CDD:214485	132/184 (72%)