Protein Alignment CG10738 and gucy1b1

DIOPT Version :10

• Sequence 1: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: NP_001238874.1
• Gene: gucy1b1 / 100150304
• ZFINID: ZDB-GENE-090313-160
• Length: 608
• Species: Danio rerio
• Alignment Length: 559
• Identity: 165/559 - (29%)
• Similarity: 235/559 - (42%)
• Gaps: 125/559 - (22%)

  Fly   616 REMKKELKLLRDARHDNICAFIGA-------CTDPP--NICIISEYCTRGSLKDILENEDVKLDN 671
            ||..:.|    ||.||::......       |||..  |..|:..|..|..|:||
Zfish    95 REFLQNL----DALHDHLGTIYPGMRAPSFRCTDAEKGNNLILHYYSEREGLQDI---------- 145

  Fly   672 MFIASMVADIIRGVI-YLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQ---GIEDSST- 731
                  |..||:.|. .:|.:.|........|......:::::..|....||.:   |.|::.|
Zfish   146 ------VIGIIKTVAQQIHGTEIEMKVIQPKSEECDHIKFLIEEKDSEEEAFYEDLDGFEENGTQ 204

  Fly   732 -------------------DMQHMSAKCLKLLYRAPELLRQGPSSL--VMGTQRGDA-YSF-GIL 773
                               |...|..:|...::|....|:.|..:|  |....|... :|| |||
Zfish   205 ETRISPYTFCKAFPFHLMFDKDLMLTQCGNAIFRVLPQLQPGVCNLSSVFSLVRPHIDFSFHGIL 269

  Fly   774 --LYEMHVRRGPFG-----------ETGLTPMQCL----QKVLQP--QDYLNPYRPSLQPLETAF 819
              :..:.|.|...|           |...|.:.||    |.:..|  ::.|....||:..|:..
Zfish   270 SHINTVFVLRSKEGLLNVETAENEDELTGTEISCLRLKGQMISLPETENILFLCSPSVMNLDDL- 333

  Fly   820 DCVSECLRECWAERPEDRPDFKTIRTKLRPLRKGMRPNIFDNMMAMME-KYANNLEALVDDRTDQ 883
                       ..|.....|.        ||....|..:........| |....||.|    ||:
Zfish   334 -----------TRRGLYLSDI--------PLHDATRDLVLLGEQFREEYKLTQELEIL----TDR 375

  Fly   884 LQ-------EEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAM-----SA 936
            ||       :||||||.||:.:||..||::|:....|..:.|:.|:|.||.||||.|.     ||
Zfish   376 LQHTLRALEDEKKKTDRLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASA 440

  Fly   937 ECTPLQVVDFLNDLYTCFDSIIGHYD---VYKVETIGDAYMVVSGLPLRNGDLHAAEIATMSLHL 998
            | ..:::|:.|||:||.||.:.....   ||||||:||.||.||||| .....||..|..::|.:
Zfish   441 E-GAIKIVNLLNDIYTRFDILTDSRKNPYVYKVETVGDKYMTVSGLP-EPCTHHAKSICHLALDM 503

  Fly   999 LSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCS 1063
            :....:.|:...|..   :.||||:|.|..||:|.:||||||||:|||..||.|::|...||:.|
Zfish   504 MEIAGQVKVDEDPVQ---ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVS 565

  Fly  1064 ---WQCRQLLDRLG-GYHFAERGVISMKGKGDQRTYWLL 1098
               ::|.|.::... .:|...||.::||||.:....|.|
Zfish   566 EYTYRCLQSVENADPQFHLEYRGPVTMKGKKEPMKVWFL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10738	NP_729905.2	PBP1_SAP_GC-like	41..441	CDD:380593
		PK_GC-A_B	570..853	CDD:270944	61/292 (21%)
		HNOBA	<860..907	CDD:462234	21/54 (39%)
		CYCc	886..1078	CDD:214485	85/203 (42%)
gucy1b1	NP_001238874.1	HNOB	2..166	CDD:462233	23/90 (26%)
		HNOBA	207..406	CDD:462234	53/222 (24%)
		Guanylate_cyc	412..605	CDD:425528	81/198 (41%)