DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10116 and lpl

DIOPT Version :9

Sequence 1:	NP_648652.1	Gene:	CG10116 / 39515	FlyBaseID:	FBgn0036367	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_571202.1	Gene:	lpl / 30354	ZFINID:	ZDB-GENE-990415-139	Length:	511	Species:	Danio rerio

Alignment Length:	335	Identity:	83/335 - (24%)
Similarity:	155/335 - (46%)	Gaps:	80/335 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TLTIAAVYG------------ETGFFLNTRRVQEN--AQPIEAEVEALVRSSFYAADPTVVTIPR 62
            ::|::.:.|            |:.|...|....|:  ...:..:.:::...:|.....|.:.|..
Zfish    36 SITLSDIIGNATEWMMDFTDIESKFSFRTLEEPEDDLCYIVPGQPQSIKDCNFNTETKTFIVIHG 100

  Fly    63 W-LGNISSPEIPAVVSARLQQQDS-NIISVD-LSEANDE-------TEII-DSVASLVIVLHNQF 116
            | :..:....:|.:|:|..:::.| |:|.|| ||.|...       |::: ..||..|..|..:.
Zfish   101 WTVTGMFESWVPKLVTALYEREPSANVIVVDWLSRAQQHYPTSASYTKLVGKDVAKFVNWLQAEI 165

  Fly   117 DMPLDRILVVGFAEGAHLAG--GVAAKVQQDLGRQLSQITALDPSSGAELDH-----KLSQADAE 174
            |.|.:::.::|::.|||:||  |:..|      .::::||.:|| :|...::     .||..||.
Zfish   166 DYPWEKLHLLGYSLGAHVAGIAGLLTK------HKVNRITGMDP-AGPTFEYADSLSTLSPDDAN 223

  Fly   175 FVEVVHTNAGGE-----GTWERLGHVDYYPNGGQTQPGC----------TTD--------SCSHE 216
            ||:|:|||..|.     |....:||:|.|||||..||||          ||.        .||||
Zfish   224 FVDVLHTNTRGSPDRSIGIQRPVGHIDIYPNGGTFQPGCDLQNTMLMVATTGLRNMDQIVKCSHE 288

  Fly   217 RAFELLAE-MWSPENDFVSARCGSVETLSAS---SCR--------WSTHKMGQKQEEEQPASGIY 269
            |:..|..: :.:.:::.::.||.|.::.:..   |||        ::.:|:..::..:.
Zfish   289 RSIHLFIDSLVNQDHESMAFRCSSRDSFNKGMCLSCRKNRCNKVGYAVNKIRTRRSSKM------ 347

  Fly   270 FLETRQSSPF 279
            :::||:..|:
Zfish   348 YMKTREMMPY 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10116	NP_648652.1	Abhydrolase	24..274	CDD:304388	77/304 (25%)
lpl	NP_571202.1	lipo_lipase	52..492	CDD:132274	81/319 (25%)
		Pancreat_lipase_like	56..353	CDD:238363	79/309 (26%)
		PLAT	360..484	CDD:294016
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010