DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10116 and Lipg

DIOPT Version :9

Sequence 1:	NP_648652.1	Gene:	CG10116 / 39515	FlyBaseID:	FBgn0036367	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	68/261 - (26%)
Similarity:	116/261 - (44%)	Gaps:	61/261 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 WLGNISSPEIPAVVSARLQQQDSNIISVD--------LSEANDETEIID-SVASLVIVLHNQFDM 118
            ||..:       |.:.:.:::::|::.||        ..:|...|.::. .||.::..|..:.:.
  Rat   103 WLHKL-------VSALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQEKGEF 160

  Fly   119 PLDRILVVGFAEGAHLAGGVAAKVQQDLGRQLSQITALDPS----SGAELDHKLSQADAEFVEVV 179
            .|..:.::|::.|||:||.....|:..:||    ||.|||:    .|.:::.:||..||:||:|:
  Rat   161 SLGDVHLIGYSLGAHVAGYAGNFVKGTVGR----ITGLDPAGPMFEGVDINRRLSPDDADFVDVL 221

  Fly   180 HT---NAG-GEGTWERLGHVDYYPNGGQTQPGCTTD---------------SCSHERAFELLAE- 224
            ||   :.| ..|....:||:|.|||||..||||..:               .|.||||..|..:
  Rat   222 HTYTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDS 286

  Fly   225 -----------MWSPENDFVSARCGSVETLSASSCRWSTHKMGQKQEEEQPASGIYFLETRQSSP 278
                       ..:..|.|....|.|......::..::..||.:|:..:.      :|:||...|
  Rat   287 LVNQDKPSFAFQCTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM------YLKTRAGMP 345

  Fly   279 F 279
            |
  Rat   346 F 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10116	NP_648652.1	Abhydrolase	24..274	CDD:304388	64/254 (25%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	65/255 (25%)
		lipo_lipase	53..488	CDD:132274	68/261 (26%)
		Heparin-binding. /evidence=ECO:0000250	327..339		3/17 (18%)
		PLAT_LPL	349..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010