Protein Alignment CG10116 and LIPH

DIOPT Version :10

• Sequence 1: NP_648652.1
• Gene: CG10116 / 39515
• FlyBaseID: FBgn0036367
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_640341.1
• Gene: LIPH / 200879
• HGNCID: 18483
• Length: 451
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 90/326 - (27%)
• Similarity: 140/326 - (42%)
• Gaps: 73/326 - (22%)

  Fly    16 AAVYGETG----FFLNTRRVQENAQPIEA----EVEALVRSSF--YAADPTVVTIPRWLGNISSP 70
            :||.| ||    ..|.||:....||.|.:    .:....:::|  :...|| .:.|.|:.::
Human    32 SAVVG-TGLNVRLMLYTRKNLTCAQTINSSAFGNLNVTKKTTFIVHGFRPT-GSPPVWMDDL--- 91

  Fly    71 EIPAVVSARLQQQDSNIISVDLSEANDETEIIDSVAS-----LVIVLHNQFDM------PLDRIL 124
                 |...|..:|.|::.||.:..  .|.:|.:.||     :.:||....|.      .||.|.
Human    92 -----VKGLLSVEDMNVVVVDWNRG--ATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLDDIY 149

  Fly   125 VVGFAEGAHLAGGVAAKVQQDLGRQLSQITALDPS----SGAELDHKLSQADAEFVEVVHTNAGG 185
            ::|.:.|||::|.|.......|||    ||.|||:    :|.....:|..:||:||:|:|::...
Human   150 MIGVSLGAHISGFVGEMYDGWLGR----ITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDA 210

  Fly   186 EGTWERLGHVDYYPNGGQTQPGCTTD--------SCSHERAFEL-----------LAEMWSPEND 231
            .|..|.||::|:|||||..||||...        .|.|:|:..|           .|.......|
Human   211 LGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQD 275

  Fly   232 FVSARCGSVETLSASSC--------RWSTHKMGQKQEEEQPASGIYFLETRQSSPFSRGAYFISF 288
            :.:.:|.|..|....||        .|..|..|    ::.|.:..:| :|.:.|||....||:..
Human   276 YRNGKCVSCGTSQKESCPLLGYYADNWKDHLRG----KDPPMTKAFF-DTAEESPFCMYHYFVDI 335

  Fly   289 L 289
            :
Human   336 I 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10116	NP_648652.1	alpha/beta hydrolases	24..274	CDD:473884	79/297 (27%)
LIPH	NP_640341.1	Pancreat_lipase_like	39..303	CDD:238363	74/278 (27%)